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Fluorescein-MAP2K1 DFS Item

Fluorescein-MAP2K1

Supplier:  Thermo Fisher Scientific PV4812

Numéro de catalogue. PV4812


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Description

Description

Inactive MAP2K1 (MEK1) has been labeled with fluorescein, and is a substrate for MAPK family members.

For use in combination with the LanthaSreen™ Tb-MAP2K1 [pSer217/221] Antibody (PV4813) to evaluate inhibitors in medium to high throughput screening applications.
Spécifications

Spécifications

Biochemical terbium phospho-specific activity
Fluorescence
MAP2K1
Kinase Substrate
10454, 10746, 1326, 4215, 4217, 4293, 4294, 4296, 5894, 673, 6885
50000 Da
MAP3K2, RAF1 (cRAF) Y340D Y341D, MAP3K10, MAP3K9, MAP3K7/MAP3K7IP1, MAP3K5, MAP3K11, BRAF V599E, BRAF, MAP3K8, MAP3K3
Fluorescein-MAP2K1 protein substrate in 10 mM Tris, pH 7.5, 150 mM NaCl, 10% glycerol, 1mM DTT. Store at -80°C.
20 nmol
Protein-Based Substrate
Serine/Threonine Kinases
FITC (Fluorescein)
Dry Ice
BRAF, MAP3K2, MAP3K3, MAP3K5, MAP3K7, MAP3K8, MAP3K9, MAP3K10, MAP3K11
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For Research Use Only. Not for use in diagnostic procedures.