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Fluorescein-ERM (LRRKtide)

Catalog No. PV4901
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PV4901 1 mg
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Catalog No. PV4901 Supplier Thermo Fisher Scientific Supplier No. PV4901
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Description

Fluorescein-ERM (LRRKtide)

A fluorescein-labeled peptide substrate based upon ezrin/radixin/moesin (ERM) that is phosphorylated by LRRK2 and LRRK2 mutants.

For use in combination with the LanthaScreen™ Tb-anti-ERM (pLRRKtide) Antibody (PV4899) to evalute inhibitors in medium to high throughput screening applications.

Specifications

Amino Acid Sequence Fluorescein-GAGRLGRDKYKTLRQIRQ
Assay Entry Biochemical terbium phospho-specific activity
Content And Storage 400 μM Fluorescein-ERM (LRRKtide) peptide substrate in water. Store at -20°C and protect from light.
Detection Method Fluorescence
Quantity 1 mg
Substrate ERM (LRRKtide)
Substrate Properties Peptide-Based Substrate
Substrate Type Kinase Substrate
Target Enzyme Serine/Threonine Kinases
Gene ID (Entrez) 120892
Label or Dye FITC (Fluorescein)
Molecular Weight (g/mol) 2475.8 Da
Shipping Condition Dry Ice
Target Entry LRRK2 D1994A, LRRK2 R1441C, LRRK2 I2020T, LRRK2 G2019S, LRRK2
Validated Kinases LRRK2
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For Research Use Only. Not for use in diagnostic procedures.