Thermo Scientific™ RNase A, DNase and protease-free (10 mg/mL)
Specifically degrade single-stranded RNA at C and U residues with the endoribonuclease RNase A.
Manufacturer: Thermo Scientific™ EN0531
RNase A, DNase and protease-free is an endoribonuclease that specifically degrades single-stranded RNA at C and U residues.
It cleaves the phosphodiester bond between the 5'-ribose of a nucleotide and the phosphate group attached to the 3'-ribose of an adjacent pyrimidine nucleotide. The resulting 2', 3'-cyclic phosphate is hydrolyzed to the corresponding 3'-nucleoside phosphate (see References 1, 2).
- RNase A is free of DNase activity. It is not necessary to heat it before use.