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Tocris Bioscience™ Favipiravir

Numéro de catalogue. 722550
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50 mg
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Numéro de catalogue. Quantity
722550 50 mg
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Numéro de catalogue. 722550 Fournisseur Tocris Bioscience™ Code fournisseur 7225/50
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Description

Viral RNA polymerase inhibitor

Favipiravir is a viral RNA polymerase inhibitor; exhibits no effects on mammalian RNA polymerase. Prodrug that is phosphoribosylated by cellular enzymes to its active form, Favipiravir-ribofuranosyl-5'-triphosphate (RTP). Reduces infection rate of SARS-CoV-2 in Vero E6 cells in vitro (IC50 = 61.88 μM). Inhibits influenza virus RNA-dependent RNA polymerase (RdRP) activity (IC50 = 341 nM). Induces lethal mutagenesis in MDCK cells inoculated with seasonal influenza A (H1N1) viruses. Protects mice against Ebola virus.

Spécifications

Chemical Name or Material 6-Fluoro-3,4-dihydro-3-oxo-2-pyrazinecarboxamide
CAS 259793-96-9
Quantity 50 mg
Target RNA/DNA Polymerase Inhibitors
Molecular Formula C5H4FN3O2
Purity 0.98