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ERM (LRRKtide) Substrate

Catalog No. PV5093
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PV5093 1 mL
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Catalog No. PV5093 Supplier Thermo Fisher Scientific Supplier No. PV5093
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Description

ERM (LRRKtide) Substrate

A peptide substrate based upon ezrin/radixin/moesin (ERM) that is phosphorylated by LRRK2 and LRRK2 mutants. For use with the Adapta™ Universal Kinase Assay (PV5099).

Specifications

Amino Acid Sequence RLGRDKYKTLRQIRQ
Assay Entry Biochemical ADP accumulation
Content And Storage 2 mM ERM (LRRKtide) peptide substrate in 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2 and 1 mM EGTA. Store at -20°C.
Detection Method Fluorescence
Quantity 1 mL
Substrate peptide based upon ezrin/radixin/moesin (ERM)
Substrate Properties Peptide-Based Substrate
Substrate Type Kinase Substrate
Target Enzyme Serine/Threonine Kinases
Gene ID (Entrez) 120892
Molecular Weight (g/mol) 1931.2 Da
Shipping Condition Dry Ice
Target Entry LRRK2 G2019S, LRRK2
Validated Kinases LRRK2
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For Research Use Only. Not for use in diagnostic procedures.