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Thermo Scientific™ Endonuclease V, T.maritima (5 U/μL)

Catalog No. FEREN0141
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FEREN0141 250 units
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Catalog No. FEREN0141 Supplier Thermo Scientific™ Supplier No. EN0141
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Description

Degrade DNA with Endonuclease V, T. maritima (Endo V), a 3'-endonuclease involved in DNA repair that initiates removal of deaminated bases from damaged DNA.

Endonuclease V, T. maritima (Endo V) is a 3'-endonuclease involved in DNA repair, which initiates removal of deaminated bases from damaged DNA, including uracil, hypoxanthine, and xanthine (see Figure 1).

Endonuclease V is also active toward abasic sites and urea sites, base pair mismatches, flap and pseudo Y structures, and small insertions/deletions in DNA molecules. The cleavage site generated by Endonuclease V is at the second phosphodiester bond 3' to a lesion. 

Highlights

  • Optimal activity at temperatures of 65 to 70°C

Specifications

Concentration 5 U/μL
Enzyme Endonuclease
Quantity 250 units
Product Type Endonuclease V

For Research Use Only. Not for use in diagnostic procedures.