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Thermo Scientific™ Endonuclease V, T.maritima (5 U/μL)
Degrade DNA with Endonuclease V, T. maritima (Endo V), a 3'-endonuclease involved in DNA repair that initiates removal of deaminated bases from damaged DNA.
Supplier: Thermo Scientific™ EN0141
Description
Endonuclease V, T. maritima (Endo V) is a 3'-endonuclease involved in DNA repair, which initiates removal of deaminated bases from damaged DNA, including uracil, hypoxanthine, and xanthine (see Figure 1).
Endonuclease V is also active toward abasic sites and urea sites, base pair mismatches, flap and pseudo Y structures, and small insertions/deletions in DNA molecules. The cleavage site generated by Endonuclease V is at the second phosphodiester bond 3' to a lesion.
Highlights
- Optimal activity at temperatures of 65 to 70°C
Specifications
| 5 U/μL | |
| Endonuclease | |
| 250 units | |
| Endonuclease V |
For Research Use Only. Not for use in diagnostic procedures.