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Tocris Bioscience™ dTRIM 24

Catalog No. 66075
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66075 5 mg
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Catalog No. 66075 Supplier Tocris Bioscience™ Supplier No. 6607/5*
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Description

TRIM24 Degrader (PROTAC™)

Degrader (PROTAC®) composed of the TRIM24 ligand IACS-9571 conjugated to a VHL ligand. Displays dose- and time-dependent degradation of TRIM24 in cells, with maximum degradation achieved at 5 μM. Degradation phenotypically mirrors genetic deletion of TRIM24. Demonstrates antiproliferative effects in MOLM-13 cells. Cell permeable.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Specifications

CAS 2170695-14-2
Quantity 5 mg
Molecular Formula C55H68N8O13S2
Formula Weight 1113.3
Product Type Degrader
Purity 98%