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  6. Thermo Scientific™ DSS (disuccinimidyl suberate), No-Weigh™ Format

Thermo Scientific™ DSS (disuccinimidyl suberate), No-Weigh™ Format

Catalog No. PIA39267
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50 mg
10 x 2 mg
1 g
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Catalog No. Quantity
PIA39267 10 x 2 mg
PI21655 50 mg
PI21555 1 g
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Catalog No. PIA39267 Supplier Thermo Scientific™ Supplier No. A39267
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Description

Crosslink amines to amines with disuccinimidyl suberate composed of NHS-ester groups with a membrane-permeable, mid-length spacer for intracellular protein crosslinking.

Thermo Scientific™ Pierce DSS, also called disuccinimidyl suberate, is noncleavable and membrane permeable crosslinker that contains an amine-reactive N-hydroxysuccinimide (NHS) ester at each end of an 8-carbon spacer arm.

  • Reactive groups: NHS ester (both ends)
  • Reactive towards: amino groups (primary amines)
  • Amine reactive sulfo-NHS ester reacts rapidly with any primary amine-containing molecule
  • Membrane-permeable, allowing for intracellular crosslinking
  • High purity, crystalline reagent can be used to create high-purity conjugates
  • Non-cleavable
  • Water-insoluble (dissolve first in DMF or DMSO); compare to BS3 (Sulfo-DSS)

Specifications

Chemical Reactivity Amine-Amine
Cleavable No
Description DSS
Molecular Weight (g/mol) 368.35
PEGylated No
Spacer Arm Length 11.4 Å
Content And Storage Upon receipt store desiccated at 4°C.
Cell Permeability Yes
Shipping Condition Ambient
Product Line No-Weigh
Labeling Method Chemical Labeling
Crosslinker Type Homobifunctional
Reactive Moiety NHS Ester
Spacer Medium (10 to 30 Å)
Form Solid
Quantity 10 x 2 mg
Solubility DMF, DMSO
Format Standard, Single-use
Water Soluble No
Product Type Crosslinker
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For Research Use Only. Not for use in diagnostic procedures.