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Dipyridamole

An inhibitor of adenosine transport and phosphodiesterase | CAS: 58-32-2 | C24H40N8O4 | 504.636 g/mol

Supplier:  Thermo Scientific Chemicals J6332914

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Catalog No. AAJ6332914


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Description

Description

Dipyridamole prevents platelets sticking to the replacement heart valve and causing a blood clot on the valve. It is used to dilate blood vessels in people with peripheral arterial disease and coronary artery disease. This compound has been shown to suppress high glucose-induced osteopontin mRNA expression and protein secretion, as well as inhibit cAMP and cGMP hydrolysis. Research indicates that Dipyridamole is a non-specific nucleoside transport inhibitor with the ability to increase the effects of adenosine in sinoatrial and atrioventricular nodes. Dipyridamole is an inhibitor of ENT1 and ENT2.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Dipyridamole prevents platelets sticking to the replacement heart valve and causing a blood clot on the valve. It is used to dilate blood vessels in people with peripheral arterial disease and coronary artery disease. This compound has been shown to suppress high glucose-induced osteopontin mRNA expression and protein secretion, as well as inhibit cAMP and cGMP hydrolysis. Research indicates that Dipyridamole is a non-specific nucleoside transport inhibitor with the ability to increase the effects of adenosine in sinoatrial and atrioventricular nodes. Dipyridamole is an inhibitor of ENT1 and ENT2.

Solubility
Soluble in chloroform, methanol, dilute acids, ethanol. Slightly soluble in water.

Notes
Store in a cool dry place. Keep away from oxidizing agents.
Specifications

Specifications

Dipyridamole
165°C to 167°C
C24H40N8O4
25 g
dipyridamole, dipyridamine, persantin, dipyridamol, dipyudamine, persantine, curantyl, stimolcardio, cardoxin, kurantil
IZEKFCXSFNUWAM-UHFFFAOYSA-N
2-[[2-[bis(2-hydroxyethyl)amino]-4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol
3108
504.63
58-32-2
Yellow
MFCD00010555
14,3346
Soluble in chloroform,methanol,dilute acids,ethanol. Slightly soluble in water.
C1CCN(CC1)C2=NC(=NC3=C2N=C(N=C3N4CCCCC4)N(CCO)CCO)N(CCO)CCO
504.636
CHEBI:4653
Powder

Chemical Identifiers

58-32-2
504.636
IZEKFCXSFNUWAM-UHFFFAOYSA-N
3108
2-[[2-[bis(2-hydroxyethyl)amino]-4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol
C24H40N8O4
MFCD00010555
dipyridamole, dipyridamine, persantin, dipyridamol, dipyudamine, persantine, curantyl, stimolcardio, cardoxin, kurantil
CHEBI:4653
C1CCN(CC1)C2=NC(=NC3=C2N=C(N=C3N4CCCCC4)N(CCO)CCO)N(CCO)CCO
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Safety and Handling

Safety and Handling

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c

H315-H319-H335

EINECSNumber : 200-374-7

RTECSNumber : KK7450000

TSCA : No

Recommended Storage : Ambient temperatures

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RUO – Research Use Only