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Dipyridamole
An inhibitor of adenosine transport and phosphodiesterase | CAS: 58-32-2 | C24H40N8O4 | 504.636 g/mol
Supplier: Thermo Scientific Chemicals J6332906
Description
Dipyridamole prevents platelets sticking to the replacement heart valve and causing a blood clot on the valve. It is used to dilate blood vessels in people with peripheral arterial disease and coronary artery disease. This compound has been shown to suppress high glucose-induced osteopontin mRNA expression and protein secretion, as well as inhibit cAMP and cGMP hydrolysis. Research indicates that Dipyridamole is a non-specific nucleoside transport inhibitor with the ability to increase the effects of adenosine in sinoatrial and atrioventricular nodes. Dipyridamole is an inhibitor of ENT1 and ENT2.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsDipyridamole prevents platelets sticking to the replacement heart valve and causing a blood clot on the valve. It is used to dilate blood vessels in people with peripheral arterial disease and coronary artery disease. This compound has been shown to suppress high glucose-induced osteopontin mRNA expression and protein secretion, as well as inhibit cAMP and cGMP hydrolysis. Research indicates that Dipyridamole is a non-specific nucleoside transport inhibitor with the ability to increase the effects of adenosine in sinoatrial and atrioventricular nodes. Dipyridamole is an inhibitor of ENT1 and ENT2.
Solubility
Soluble in chloroform, methanol, dilute acids, ethanol. Slightly soluble in water.
Notes
Store in a cool dry place. Keep away from oxidizing agents.
Specifications
| Dipyridamole | |
| 165°C to 167°C | |
| C24H40N8O4 | |
| 5 g | |
| dipyridamole, dipyridamine, persantin, dipyridamol, dipyudamine, persantine, curantyl, stimolcardio, cardoxin, kurantil | |
| IZEKFCXSFNUWAM-UHFFFAOYSA-N | |
| 2-[[2-[bis(2-hydroxyethyl)amino]-4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol | |
| 3108 | |
| 504.63 |
| 58-32-2 | |
| Yellow | |
| MFCD00010555 | |
| 14,3346 | |
| Soluble in chloroform,methanol,dilute acids,ethanol. Slightly soluble in water. | |
| C1CCN(CC1)C2=NC(=NC3=C2N=C(N=C3N4CCCCC4)N(CCO)CCO)N(CCO)CCO | |
| 504.636 | |
| CHEBI:4653 | |
| Powder |
Chemical Identifiers
| 58-32-2 | |
| 504.636 | |
| IZEKFCXSFNUWAM-UHFFFAOYSA-N | |
| 3108 | |
| 2-[[2-[bis(2-hydroxyethyl)amino]-4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol |
| C24H40N8O4 | |
| MFCD00010555 | |
| dipyridamole, dipyridamine, persantin, dipyridamol, dipyudamine, persantine, curantyl, stimolcardio, cardoxin, kurantil | |
| CHEBI:4653 | |
| C1CCN(CC1)C2=NC(=NC3=C2N=C(N=C3N4CCCCC4)N(CCO)CCO)N(CCO)CCO |
Safety and Handling
GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
H315-H319-H335
EINECSNumber : 200-374-7
RTECSNumber : KK7450000
TSCA : No
Recommended Storage : Ambient temperatures
RUO – Research Use Only