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Chloromethyl chloroformate, 97%
CAS: 22128-62-7 | C2H2Cl2O2 | 128.936 g/mol
Supplier: Thermo Scientific Chemicals L0952709
Description
Chloromethyl chloroformate is used as an intermediate in pharmaceuticals and in manufacture other chemicals. It acts as a reactant in the synthesis of aminocarbonyloxymethyl esters of diclofenac, flufenamic acid and in monomethoxypoly(ethyleneglycol) prodrugs of cyclosporin A.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsChloromethyl chloroformate is used as an intermediate in pharmaceuticals and in manufacture other chemicals. It acts as a reactant in the synthesis of aminocarbonyloxymethyl esters of diclofenac, flufenamic acid and in monomethoxypoly(ethyleneglycol) prodrugs of cyclosporin A.
Solubility
Slightly miscible with water.
Notes
Incompatible with oxidizing agents and water.
Specifications
| Chloromethyl chloroformate | |
| <-20°C | |
| 107°C to 108°C | |
| Acrid | |
| 1.4295 | |
| MFCD00077688 | |
| UN2745 | |
| Moisture sensitive | |
| Slightly miscible with water. | |
| C(OC(=O)Cl)Cl | |
| 128.936 | |
| 128.94 |
| 22128-62-7 | |
| 1.465 | |
| 95°C (203°F) | |
| C2H2Cl2O2 | |
| ClCO2CH2Cl | |
| 10 g | |
| 506426 | |
| chloromethyl chloroformate, chloromethylchloroformate, chloroformic acid chloromethyl ester, carbonochloridic acid, chloromethyl ester, palite, chlormethylchlorformiat, clco2ch2cl, chlormethylchlorocarbonat, chloromethyl choroformate, choromethyl chloroformate | |
| JYWJULGYGOLCGW-UHFFFAOYSA-N | |
| chloromethyl carbonochloridate | |
| 62754 | |
| 97% |
Chemical Identifiers
| 22128-62-7 | |
| 128.936 | |
| JYWJULGYGOLCGW-UHFFFAOYSA-N | |
| 62754 | |
| C(OC(=O)Cl)Cl |
| C2H2Cl2O2 | |
| MFCD00077688 | |
| chloromethyl chloroformate, chloromethylchloroformate, chloroformic acid chloromethyl ester, carbonochloridic acid, chloromethyl ester, palite, chlormethylchlorformiat, clco2ch2cl, chlormethylchlorocarbonat, chloromethyl choroformate, choromethyl chloroformate | |
| chloromethyl carbonochloridate |
Safety and Handling
GHS H Statement
H331-H314-H318-H302
Toxic if inhaled.
Causes severe skin burns and eye damage.
Causes serious eye damage.
Harmful if swallowed.
P260-P264b-P270-P271-P280-P284-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P501c
H302-H314-H330-H335
DOTInformation : Transport Hazard Class: 6.1; Packing Group: II; Proper Shipping Name: CHLOROMETHYL CHLOROFORMATE
EINECSNumber : 244-793-3
TSCA : No
Recommended Storage : Keep cold
RUO – Research Use Only