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Chloromethyl chloroformate, 97%

CAS: 22128-62-7 | C2H2Cl2O2 | 128.936 g/mol

$188.89 - $676.11

Chemical Identifiers

CAS 22128-62-7
Molecular Formula C2H2Cl2O2
Molecular Weight (g/mol) 128.936
MDL Number MFCD00077688
InChI Key JYWJULGYGOLCGW-UHFFFAOYSA-N
Synonym chloromethyl chloroformate, chloromethylchloroformate, chloroformic acid chloromethyl ester, carbonochloridic acid, chloromethyl ester, palite, chlormethylchlorformiat, clco2ch2cl, chlormethylchlorocarbonat, chloromethyl choroformate, choromethyl chloroformate
PubChem CID 62754
IUPAC Name chloromethyl carbonochloridate
SMILES C(OC(=O)Cl)Cl
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
AAL0952709
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Thermo Scientific Chemicals
L0952709
10 g
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AAL0952718
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Thermo Scientific Chemicals
L0952718
50 g
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Description

Description

Chloromethyl chloroformate is used as an intermediate in pharmaceuticals and in manufacture other chemicals. It acts as a reactant in the synthesis of aminocarbonyloxymethyl esters of diclofenac, flufenamic acid and in monomethoxypoly(ethyleneglycol) prodrugs of cyclosporin A.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Chloromethyl chloroformate is used as an intermediate in pharmaceuticals and in manufacture other chemicals. It acts as a reactant in the synthesis of aminocarbonyloxymethyl esters of diclofenac, flufenamic acid and in monomethoxypoly(ethyleneglycol) prodrugs of cyclosporin A.

Solubility
Slightly miscible with water.

Notes
Incompatible with oxidizing agents and water.
Specifications

Chemical Identifiers

22128-62-7
128.936
JYWJULGYGOLCGW-UHFFFAOYSA-N
62754
C(OC(=O)Cl)Cl
C2H2Cl2O2
MFCD00077688
chloromethyl chloroformate, chloromethylchloroformate, chloroformic acid chloromethyl ester, carbonochloridic acid, chloromethyl ester, palite, chlormethylchlorformiat, clco2ch2cl, chlormethylchlorocarbonat, chloromethyl choroformate, choromethyl chloroformate
chloromethyl carbonochloridate

Specifications

22128-62-7
1.465
95°C (203°F)
C2H2Cl2O2
ClCO2CH2Cl
10 g
506426
chloromethyl chloroformate, chloromethylchloroformate, chloroformic acid chloromethyl ester, carbonochloridic acid, chloromethyl ester, palite, chlormethylchlorformiat, clco2ch2cl, chlormethylchlorocarbonat, chloromethyl choroformate, choromethyl chloroformate
JYWJULGYGOLCGW-UHFFFAOYSA-N
chloromethyl carbonochloridate
62754
97%
<-20°C
107°C to 108°C
Acrid
1.4295
MFCD00077688
UN2745
Moisture sensitive
Slightly miscible with water.
C(OC(=O)Cl)Cl
128.936
128.94
Chloromethyl chloroformate
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Safety and Handling

Safety and Handling

GHS H Statement
H331-H314-H318-H302
Toxic if inhaled.
Causes severe skin burns and eye damage.
Causes serious eye damage.
Harmful if swallowed.

P260-P264b-P270-P271-P280-P284-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P501c

H302-H314-H330-H335

DOTInformation : Transport Hazard Class: 6.1; Packing Group: II; Proper Shipping Name: CHLOROMETHYL CHLOROFORMATE

EINECSNumber : 244-793-3

TSCA : No

Recommended Storage : Keep cold

SDS
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RUO – Research Use Only