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Invitrogen™ CDK2/cyclin E1 Recombinant Human Protein DFS Item

CDK2 is a member of the Cyclin-Dependent Kinase family that is ubiquitously expressed. Recombinant full-length human CDK2 and CyclinE1 were co-expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag on both proteins.

$590.00 - $9,080.00

Specifications

Host Species Human
Protein Tag GST Tag
Recombinant Yes
View More Specs

Products 3
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
PV6295 View Documents Invitrogen™
LSPV6295
10μg Each for $590.00
 
PV6296 View Documents Invitrogen™
LSPV6296
100μg Each for $2,030.00
 
PV6297 View Documents Invitrogen™
LSPV6297
1mg Each for $9,080.00
 
Description

Description

CDK2 is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. CDK2 associates with and is regulated by the regulatory subunits of the complex including Cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). CDK2 phosphorylates multiple cellular substrates including SMAD3 and FOXO1. Phosphorylation of FOXO1 leads to its inhibition.

  • Validated in LanthaScreen™ Kinase Binding Assay
  • Protocols available for simple use and optimized performance
  • Multiple pack sizes available for convenient use
Specifications

Specifications

Human
GST Tag
Yes