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CCF4-AM DFS Item

CCF4-AM

$37980.00 - $103400.00

Specifications

Cell Permeability Cell-Permeant
Content And Storage Store in freezer (-5 to -30°C).
Detection Method Fluorescence
Form Solid
Substrate CCF4-AM
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
K1029 DFS Item
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Thermo Fisher Scientific
K1029
20mg N/A
N/A
Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.
K1028 DFS Item
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Thermo Fisher Scientific
K1028
5mg N/A
N/A
Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.
Description

Description

CCF4-AM, our LiveBLAzer™ substrate, is a lipophilic, esterified form of the CCF4 substrate which allows it to readily enter cells. Upon entry, cleavage by endogenous cytoplasmic esterases rapidly converts CCF4-AM into its negatively charged form, CCF4, which is retained in the cytosol. CCF4 is a Fluorescence Resonance Energy Transfer (FRET) substrate which consists of a cephalosporin core linking 7-hydroxycoumarin to fluorescein. This product is to be used as a FRET-based substrate for β-lactamase as a sensitive reporter of mammalian gene expression in the GeneBLAzer™ technology.
Specifications

Specifications

Cell-Permeant
Fluorescence
CCF4-AM
Beta-Lactamase Substrate
Room Temperature
Store in freezer (-5 to -30°C).
Solid
Chemical Substrate
Flow Cytometer, Microplate Reader
Videos
SDS
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For Research Use Only. Not for use in diagnostic procedures.