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Thermo Scientific™ CaptureSelect™ IgG-Fc (Multispecies) Magnetic Agarose Beads
Description
CaptureSelect IgG-Fc (Multispecies) Magnetic Agarose Beads are high-capacity, high-throughput magnetic affinity particles for antibody purification using manual or robotic magnetic separators. The CaptureSelect IgG-Fc (multispecies) ligand has been specifically designed to purify IgG through high-affinity binding of the IgG Fc region. These magnetic agarose beads can be used for the purification of IgG from a broad range of species. The tested species and their specificity are shown in the figure below.
Features of CaptureSelect IgG-Fc (multispecies) Magnetic Agarose Beads include:
- One-step IgG purification with high purity, from crude material
- Compatible with manual and automated workflows (e.g., Thermo Scientific KingFisher instruments)
- Short operation time
- No sample dilution required during isolation, repetitive sample loading feasible
- Non-animal-derived
Free of animal components
CaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (VHH) created by a proprietary technology. The VHH affinity ligand is a 12 to 15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (Animal Origin-Free).
Main characteristics:
- Matrix: 6% cross-linked magnetized agarose
- Average particle size: 25–30 μm
- Suspension: 25% slurry
- Ligand: CaptureSelect IgG-Fc (multispecies) affinity ligand
- Binding capacity: >4 mg IgG/mL slurry
- Elution conditions: 0.1 M glycine, pH 3.0
Specifications
Specifications
| Binding Capacity | >4 mg IgG/mL slurry |
| Matrix | 6% cross-linked magnetized agarose |
| Particle Size | 25 to 30 μm |
| Form | Resin Slurry |
| Product Line | CaptureSelect |
| Quantity | 5 mL |
| Type | Magnetic Agarose Bead |
| Ligand Type | IgG-Fc (multispecies) affinity ligand |