missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Protein Purification
  5. Protein Purification Reagents and Kits
  6. Thermo Scientific™ CaptureSelect™ IgA-XL Affinity Matrix

Thermo Scientific™ CaptureSelect™ IgA-XL Affinity Matrix
GREENER_CHOICE

Catalog No. 2943972005
missing translation for 'changeView'
missing translation for 'orderingAttributeHoverText'
Quantity:
5 mL
10 mL
2 product options available for selection
Product selection table with 2 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
2943972005 5 mL
2943972010 10 mL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 2 options available.
2 missing translation for 'options'
Catalog No. 2943972005 missing translation for 'mfr' Thermo Scientific™ missing translation for 'supplierNo' 2943972005
Only null left

Description

Thermo Scientific™ CaptureSelect™ IgA-XL Affinity Matrix is intended for the purification of human IgA, with no binding to other immunoglobulins.

CaptureSelect IgA-XL Affinity Matrix is intended for the purification of human IgA, with no binding to other immunoglobulins. The IgA-XL affinity matrix provides improved binding capacities (>15 g/L IgA) and elution characteristics (full elution at pH 4) compared to CaptureSelect IgA Affinity Matrix.

Features of this affinity matrix include:

  • Purification of all IgA serotypes: IgA1, IgA2, dimeric IgA, and S-IgA (secretory IgA)
  • IgA purification from plasma, serum, and recombinant sources
  • Efficient purification of IgA with high yields and retained activity
  • Excellent scalability
  • Non-animal-derived

CaptureSelect IgA-XL Affinity Matrix binds to the Fc part of IgA. The high selectivity and yields obtained using IgA-XL Affinity Matrix enable a robust, fast, and efficient purification process with excellent purity obtained in one step.

Animal origin statement

CaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (VHH) created by a proprietary technology. The VHH affinity ligand is a 12–15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (animal origin-free).

Main characteristics

  • Matrix: agarose-based, epoxide activated
  • Average particle size: 65 ± 10 μm
  • Ligand: CaptureSelect IgA-XL affinity ligand
  • Ligand coupling method: epoxide
  • Binding capacity: > 15 g/L at 5 minutes residence time, tested with plasma-derived polyclonal IgA
  • Elution conditions: 20 mM sodium citrate, pH 4
  • Flow characteristics: 50–200 cm/h (up to 2 bar)
  • Formulation buffer: 20% (v/v) ethanol

Specifications

Flow Rate 50–200 cm/hr. (up to 2 bar)
Formulation 20% (v/v) ethanol
Content And Storage Store at 2–8°C. Protect from direct sunlight.
Particle Size 65 ±10 μm
Form Resin Slurry
Product Line CaptureSelect
Quantity 5 mL
For Use With (Application) Purification of all IgA subtypes (IgA1, IgA2, dimeric IgA, secretory IgA)
Target IgA-Fc domain
Type Affinity Matrix
Ligand Type CaptureSelect IgA-XL Affinity Ligand
Show More Show Less