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  6. Thermo Scientific™ CaptureSelect™ Biotin CH1-XL Conjugate

Thermo Scientific™ CaptureSelect™ Biotin CH1-XL Conjugate

Catalog No. 7103462100
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7103462100 100 μg
7103462500 500 μg
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Catalog No. 7103462100 Supplier Thermo Scientific™ Supplier No. 7103462100

Description

Thermo Scientific™ CaptureSelect™ Biotin CH1-XL Conjugate consists of a 14-kDa recombinant single domain antibody fragment (VHH affinity ligand) that specifically binds to the CH1 domain of all four human IgG subclasses.

CaptureSelect Biotin CH1-XL Conjugate consists of a 14-kDa recombinant single domain antibody fragment (VHH affinity ligand) that specifically binds to the CH1 domain of all four human IgG subclasses. The affinity ligand is chemically conjugated to biotin via an appropriate spacer that retains the binding reactivity of the ligand when used in combination with streptavidin-based conjugates or streptavidin pre-coated surfaces.

CaptureSelect Biotin CH1-XL Conjugate is an improved version of CaptureSelect Biotin Anti-IgG-CH1 for applications that require target elution at a milder pH. The specificity is the same, but it features a wider elution range between pH 3.0 and 4.5.

This conjugate allows you to detect, quantitate, and characterize all human IgG antibodies (subclasses 1 to 4) and their Fab fragments, independent of light chain type, and total IgG in human plasma and/or serum samples.

Applications for CaptureSelect Biotin CH1-XL Conjugate include ELISA, western blot, Gyrolab™-based immunoassays, immunoprecipitation with streptavidin-coupled Dynabeads, and label-free detection platforms such as those based on surface plasmon resonance (Biacore™ and IBIS-MX96 systems) and bio-layer interferometry (ForteBio™ Octet™ systems).

Animal origin statement

CaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (VHH) created by a proprietary technology. The VHH affinity ligand is a 12–15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (Animal Origin-Free).

Specifications

Content And Storage Store in freezer (-5°C to -30°C).
Shipping Condition Dry Ice
Form Liquid
Product Line CaptureSelect
Quantity 100 μg
Type Conjugate
Label or Dye Biotin & Analogs
Ligand Type Antibody