Thermo Scientific™ CaptureSelect™ Biotin Anti-AAT Conjugate

Description

CaptureSelect Biotin Anti-AAT Conjugate consists of a 13 kDa recombinant single domain antibody fragment (V_HH affinity ligand) that specifically binds with high affinity and selectivity to human alpha-1 antitrypsin (AAT). The affinity ligand is chemically conjugated to biotin via an appropriate spacer that retains the binding reactivity of the ligand when used in combination with streptavidin-based conjugates or streptavidin pre-coated surfaces. This conjugate allows you to detect, quantitate, and characterize native and recombinant human AAT.

Applications for CaptureSelect Biotin Anti-AAT Conjugate include ELISA, immunoprecipitation with streptavidin-coupled DynaBeads, Gyrolab™-based immunoassays, and label-free detection using platforms such as those based on surface plasmon resonance (Biacore™ and IBIS-MX96 systems) and bio-layer interferometry (ForteBio™ Octet™ systems).

Animal origin statement

CaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (V_HH) created by a proprietary technology. The V_HH affinity ligand is a 12–15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (Animal Origin-Free).