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Tocris Bioscience™ C 176

Catalog No. 704050
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50 mg
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704050 50 mg
704010 10 mg
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Catalog No. 704050 Supplier Tocris Bioscience™ Supplier No. 7040/50
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Description

mSTING antagonist

C 176 is a mSTING antagonist. Covalently binds Cys91 of mouse but not human STING. Blocks activation-induced palmitoylation of STING and formation of STING clusters. Reduces CMA (Cat. No. 6677) -induced increase in serum IFNs in vivo and suppresses systemic inflammation in a mouse inflammatory disease model.

Specifications

CAS 314054-00-7
Quantity 50 mg
Target STING Antagonists
Molecular Formula C11H7IN2O4
Formula Weight 2929
Purity 97%