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  6. Thermo Scientific™ BS3 (bis(sulfosuccinimidyl)suberate)

Thermo Scientific™ BS3 (bis(sulfosuccinimidyl)suberate)

Catalog No. pi21586
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Quantity:
1 g
10 x 2 mg
50 mg
Catalog No. Quantity
PI21586 1 g
PIA39266 10 x 2 mg
PI21580 50 mg
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Catalog No. PI21586

Supplier: Thermo Scientific™ 21586

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Description

Crosslink amines to amines with BS3; composed of sulfo-NHS-ester groups separated by an 11.4A, water-soluble spacer arm that is useful for cell-surface protein crosslinking.

Thermo Scientific™ Pierce BS3 (Sulfo-DSS) is bis(sulfosuccinimidyl)suberate, an amine-to-amine crosslinker that is homobifunctional, water-soluble, non-cleavable and membrane impermeable.

Highlights:

  • Crosslink cell-surface proteins before cell lysis and immunoprecipitation
  • Identify receptor-ligand interactions by chemical crosslinking
  • “Fix” protein interactions to allow identification of weak or transient protein interactions
  • Identify near-neighbor protein interactions
  • Protein crosslinking to create bioconjugates via single-step reactions
  • Immobilize proteins onto amine-coated surfaces

Specifications

Chemical Reactivity Amine-Amine
Cleavable No
Molecular Weight (g/mol) 572.43
PEGylated No
Spacer Arm Length 11.4 Å
Content And Storage Upon receipt store desiccated at 4°C.
Cell Permeability No
Shipping Condition Ambient
Product Line Pierce
Labeling Method Chemical Labeling
Crosslinker Type Homobifunctional
Reactive Moiety Sulfo-NHS Ester
Spacer Medium (10 to 30 Å)
Form Powder
Quantity 1 g
Solubility Water
Format Standard, Single-use, Premium-grade
Water Soluble Yes
Product Type Crosslinker
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For Research Use Only. Not for use in diagnostic procedures.