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Tocris Bioscience™ BI 3231

Catalog No. 80395
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80395 5 mg
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Catalog No. 80395 Supplier Tocris Bioscience™ Supplier No. 8039/5
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Description

Potent and selective hydroxysteroid 17β dehydrogenase 13 (HSD17B13) inhibitor

BI 3231 is a potent and selective hydroxysteroid 17β dehydrogenase 13 (HSD17B13) inhibitor (IC50 values are 1 nM and 13 nM at hHSD17B13 and mHSD17B13 respectively; Ki = 0.7 nM). Reduces palmitic acid-induced toxicity in hepatocytes. Suitable for use in vivo and in vitro.

Specifications

Chemical Name or Material 1-[[5-(2,4-Difluoro-3-hydroxyphenyl)-1,3,4-thiadiazol-2-yl]methyl]-3-ethyl-5-methyl-2,4(1H,3H)pyrimidinedione
CAS 2894848-07-6
Quantity 5 mg
Target Dehydrogenase Inhibitors
Molecular Formula C16H14F2N4O3S
Purity 0.98