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Alfa Aesar™ Bexarotene, 99+%

Synthetic retinoid analog with specific affinity for the retinoid X receptor

$476.14 - $476.14

Chemical Identifiers

Chemical Name or Material Bexarotene
CAS 153559-49-0
Molecular Formula C24H28O2
Formula Weight 348.48
MDL Number MFCD00932428
Merck Index 14,1194
Synonym LGD-1069; Targretin
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Products
Catalog Number Mfr. No. Quantity Price Quantity    

AAJ63701EXH

  SDS
alfa aesar™
J63701EXH
300mg Each for $476.14
Description & Specifications

Specifications

Formula Weight 348.48
Chemical Name or Material Bexarotene
Molecular Formula C24H28O2
Assay ≥99%
Health Hazard 3 GHS P Statement
P261-P280-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.
MDL Number MFCD00932428
CAS 153559-49-0
Physical Form Powder
Solubility Information Soluble in DMSO and ethanol
RTECS Number DH6834830
Health Hazard 2 GHS H Statement
H302-H315-H319-H335
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Synonym LGD-1069; Targretin
Melting Point 220° to 225°C
Quantity 300mg
Recommended Storage −30° to −10°C
Merck Index 14,1194
Color White
Health Hazard 1 Warning

Applications
Bexarotene is used as a Synthetic retinoid analog with specific affinity for the retinoid X receptor, an antineoplastic agent, already approved as an oral antineoplastic agent for cutaneous T cell lymphoma and being investigated against other cancers. A study has found that bexarotene in a mouse Alzheimer′s model lowered the most toxic form of β-amyloid peptide and increased cognitive ability.

Solubility
Soluble in DMSO and ethanol

Notes
Store in cool, dry conditions in well sealed containers. Keep container tightly closed.

Safety and Handling

Warning

GHS P Statement
P261-P280-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

GHS H Statement
H302-H315-H319-H335
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

−30° to −10°C