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Alfa Aesar™ Bexarotene, 99+%

Synthetic retinoid analog with specific affinity for the retinoid X receptor

$215.89 - $507.35

Chemical Identifiers

CAS 153559-49-0
Molecular Formula C24H28O2
Molecular Weight (g/mol) 348.486
MDL Number MFCD00932428
InChI Key NAVMQTYZDKMPEU-UHFFFAOYSA-N
Synonym bexarotene, targretin, targrexin, targretyn, targret, bexarotenum, bexarotene usan, bexaroteno, bexaroten, targretin-gel
PubChem CID 82146
ChEBI CHEBI:50859
IUPAC Name 4-[1-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)ethenyl]benzoic acid
SMILES CC1=CC2=C(C=C1C(=C)C3=CC=C(C=C3)C(=O)O)C(CCC2(C)C)(C)C
View More Specs

Products 2
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
AAJ63701MC View Documents Alfa Aesar™
J63701MC
100mg Each for $215.89
 
AAJ63701EXH View Documents Alfa Aesar™
J63701EXH
300mg Each for $507.35
 
Description

Description

Applications
Bexarotene is used as a Synthetic retinoid analog with specific affinity for the retinoid X receptor, an antineoplastic agent, already approved as an oral antineoplastic agent for cutaneous T cell lymphoma and being investigated against other cancers. A study has found that bexarotene in a mouse Alzheimer′s model lowered the most toxic form of β-amyloid peptide and increased cognitive ability.

Solubility
Soluble in DMSO and ethanol

Notes
Store in cool, dry conditions in well sealed containers. Keep container tightly closed.
Specifications

Chemical Identifiers

153559-49-0
348.486
NAVMQTYZDKMPEU-UHFFFAOYSA-N
82146
4-[1-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)ethenyl]benzoic acid
C24H28O2
MFCD00932428
bexarotene, targretin, targrexin, targretyn, targret, bexarotenum, bexarotene usan, bexaroteno, bexaroten, targretin-gel
CHEBI:50859
CC1=CC2=C(C=C1C(=C)C3=CC=C(C=C3)C(=O)O)C(CCC2(C)C)(C)C

Specifications

White
100mg
C24H28O2
14,1194
Soluble in DMSO and ethanol
CC1=CC2=C(C=C1C(=C)C3=CC=C(C=C3)C(=O)O)C(CCC2(C)C)(C)C
348.486
CHEBI:50859
Powder
Bexarotene
220°C to 225°C
153559-49-0
MFCD00932428
bexarotene, targretin, targrexin, targretyn, targret, bexarotenum, bexarotene usan, bexaroteno, bexaroten, targretin-gel
NAVMQTYZDKMPEU-UHFFFAOYSA-N
4-[1-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)ethenyl]benzoic acid
82146
348.48
≥99%
Safety and Handling

Safety and Handling

GHS H Statement
H302-H315-H319-H335
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

GHS P Statement
P261-P280-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

Warning

RTECSNumber : DH6834830

Recommended Storage : −30° to −10°C