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  5. Tocris Bioscience™ Béxarotène

Tocris Bioscience™ Béxarotène

Numéro de catalogue. 581950
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50 mg
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Numéro de catalogue. Quantité
581950 50 mg
581910 10 mg
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Numéro de catalogue. 581950 Fournisseur Tocris Bioscience™ Code fournisseur 5819/50

Description

Agoniste RXR puissant et sélectif

Bexarotene is a potent and selective RXR agonist (EC50 values are 24, 25 and 33 nM for RXRβ, RXRγ and RXRα, respectively). Exhibits >300-fold selectivity for RXR over RAR receptors. Inhibits tumor cell invasion and migration in vitro, and inhibits metastasis and angiogenesis in mouse models. Also promotes brown adipogenic differentiation and induces brown adipogenic reprogramming from myoblasts.

Spécifications

Nom ou substance chimique 4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid
CAS 153559-49-0
Synonyme LGD 1069
Quantité 50 mg
Cible Retinoid X Receptor Agonists
Formule moléculaire C24H28O2
Poids de formule 348.48
Pureté >99%