Benzoic anhydride is used as a benzoylating agent in the manufacture of pharmaceuticals, dyes and intermediates. It serves as an arylation agent in the Heck reaction. It is also used to get benzoic acid through dehydration. Further, it is used to prepare furan-2-yl-phenyl-methanone, which is similar to Friedel-Crafts acylation reaction. In addition to this, it is used for the synthesis of carboxylic esters and lactones.
Soluble in alcohol, ether, chloroform, acetone, ethyl acetate, benzene, toluene, glacial acetic acid, acetic anhydride and ethanol. Slightly soluble in benzene and acetone. Insoluble in water.
Moisture sensitive. Incompatible with strong acids, strong oxidizing agents and strong bases.
Safety and Handling
GHS H Statement
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
GHS P Statement
Wear protective gloves.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
TSCA : TSCA
storageNote1 : Moisture sensitive