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Tocris Bioscience™ Aprepitant

Catalog No. 648650
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50 mg
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Catalog No. Quantity
648650 50 mg
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Catalog No. 648650 Supplier Tocris Bioscience™ Supplier No. 6486/50
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Description

Potent long-acting hNK-1 antagonist

Aprepitant is a potent long-acting hNK-1 antagonist, (IC50 = 0.09 nM and Kd = 19 pM). Inhibits induced foot-tapping in gerbils. CNS penetrant and orally bioavailable. Antiemetic.

Specifications

Chemical Name or Material 5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one
CAS 170729-80-3
Quantity 50 mg
Molecular Formula C23H21F7N4O3
Purity 99%