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Actinomycin D (1 mg/ml, DMSO)
CAS: 50-76-0 | C62H86N12O16 | 1255.438 g/mol
$370.45 - $1,107.79
Chemical Identifiers
| CAS | 50-76-0 |
|---|---|
| Molecular Formula | C62H86N12O16 |
| Molecular Weight (g/mol) | 1255.438 |
| MDL Number | MFCD00005033 |
| InChI Key | RJURFGZVJUQBHK-HUZQGMAJSA-N |
| Synonym | Dactinomycin; Actinomycin C1 |
| PubChem CID | 131954673 |
| IUPAC Name | 2-amino-4,6-dimethyl-3-oxo-1-N-[(3R,6S,7R,10S,16S)-7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-6-yl]-9-N-[(3R,6S,7R,16S)-7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4, |
| SMILES | CC1C(C(=O)NC(C(=O)N2CCCC2C(=O)N(CC(=O)N(C(C(=O)O1)C(C)C)C)C)C(C)C)NC(=O)C3=C4C(=C(C=C3)C)OC5=C(C(=O)C(=C(C5=N4)C(=O)NC6C(OC(=O)C(N(C(=O)CN(C(=O)C7CCCN7C(=O)C(NC6=O)C(C)C)C)C)C(C)C)C)N)C |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
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AAJ67160XF
|
Thermo Scientific Chemicals
J67160XF |
1 mL |
N/A
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AAJ671608EQ
|
Thermo Scientific Chemicals
J671608EQ |
5 x 1 mL |
N/A
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Description
Actinomycin D has a wide-ranging applications ranging from a selection agent in cell culture, use in studies of suppressing HIV-replication and programmed cell death of PC12 cells, and as an antibiotic in treatment of various malignant neoplasms, including Wilm?s tumor and the sarcomas.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsActinomycin D has a wide-ranging applications ranging from a selection agent in cell culture, use in studies of suppressing HIV-replication and programmed cell death of PC12 cells, and as an antibiotic in treatment of various malignant neoplasms, including Wilm′s tumor and the sarcomas.
Solubility
Soluble in acetonitrilie or acetone at 10 mg/mL and in DMSO at a minimum of 1 mg/mL, slightly soluble in water.
Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.
Chemical Identifiers
| 50-76-0 | |
| 1255.438 | |
| RJURFGZVJUQBHK-HUZQGMAJSA-N | |
| 131954673 | |
| CC1C(C(=O)NC(C(=O)N2CCCC2C(=O)N(CC(=O)N(C(C(=O)O1)C(C)C)C)C)C(C)C)NC(=O)C3=C4C(=C(C=C3)C)OC5=C(C(=O)C(=C(C5=N4)C(=O)NC6C(OC(=O)C(N(C(=O)CN(C(=O)C7CCCN7C(=O)C(NC6=O)C(C)C)C)C)C(C)C)C)N)C |
| C62H86N12O16 | |
| MFCD00005033 | |
| Dactinomycin; Actinomycin C1 | |
| 2-amino-4,6-dimethyl-3-oxo-1-N-[(3R,6S,7R,10S,16S)-7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-6-yl]-9-N-[(3R,6S,7R,16S)-7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4, |
Specifications
| Actinomycin D | |
| 50-76-0 | |
| C62H86N12O16 | |
| Dactinomycin; Actinomycin C1 | |
| RJURFGZVJUQBHK-HUZQGMAJSA-N | |
| 2-amino-4,6-dimethyl-3-oxo-1-N-[(3R,6S,7R,10S,16S)-7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-6-yl]-9-N-[(3R,6S,7R,16S)-7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4, | |
| 131954673 |
| Liquid | |
| 1 mL | |
| MFCD00005033 | |
| Soluble in acetonitrilie or acetone at 10mg/mL and in DMSO at a minimum of 1mg/mL,slightly soluble in water. | |
| CC1C(C(=O)NC(C(=O)N2CCCC2C(=O)N(CC(=O)N(C(C(=O)O1)C(C)C)C)C)C(C)C)NC(=O)C3=C4C(=C(C=C3)C)OC5=C(C(=O)C(=C(C5=N4)C(=O)NC6C(OC(=O)C(N(C(=O)CN(C(=O)C7CCCN7C(=O)C(NC6=O)C(C)C)C)C)C(C)C)C)N)C | |
| 1255.438 | |
| Actinomycin D, 1mg/mL in DMSO, sterile-filtered |
Safety and Handling
GHS H Statement
H227
Combustible liquid.
P210-P280-P370+P378q-P501c
H227
EINECSNumber : 200-063-6
RTECSNumber : AU1575000
TSCA : No
storageNote1 : -30° to -10°C
Recommended Storage : Store at -20°C
RUO – Research Use Only