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Tocris Bioscience™ Ac4ManNAz
Description
Ac4ManNAz is a cell-permeable, unnatural azide-containing monosaccharide building block. Ac4ManNAz is metabolized and incorporated as azidosialic acid into cell surface and secreted sialoglycoproteins to allow Cu(I)-free click chemistry for further conjugation or detection. Ac4ManNAz can be used for bioorthogonal labeling of human prostate tissue slice cultures; the target sialoglycoproteins can be biotinylated for proteomic analysis or reacted with a cyclooctyne-functionalized optical probe for imaging. Ac4ManNAz is also used to label glycoRNAs on the cell surface.
Spécifications
Spécifications
| Chemical Name or Material | 2-[(2-Azidoacetyl)amino]-2-deoxy-D-mannopyranose-1,3,4,6-tetraacetate |
| CAS | 361154-30-5 |
| Quantity | 10 mg |
| Target | Photoactivatable Cross-linking Probes |
| Molecular Formula | C16H22N4O10 |
| Purity | 0.95 |