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6-Chloropurine riboside, 98%
CAS: 5399-87-1 | C10H11ClN4O4 | 286.67 g/mol
Supplier: Thermo Scientific Chemicals H5963406
Description
6-Chloropurine riboside is used to study the kinetics and substrate specificity of adenosine deaminase. 6-Chloropurine riboside is benzoylated to facilitate synthesis of nucleoside derivatives such as 9-(2,3-Di-deoxy-2-fluoro-β-D-threo-pentofuranosyl)adenine. It , especially after phosphorylation to NMP, NDP or NTP, is used as a purine substrate analogue in studies with enzymes such as Inosine monophosphate dehydrogenase (IMPDH); bacteriophage T4 RNA-ligase (EC 6.5.1.3) and pancreatic fibonuclease A.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications6-Chloropurine riboside is used to study the kinetics and substrate specificity of adenosine deaminase. 6-Chloropurine riboside is benzoylated to facilitate synthesis of nucleoside derivatives such as 9-(2,3-Di-deoxy-2-fluoro-β-D-threo-pentofuranosyl)adenine. It , especially after phosphorylation to NMP, NDP or NTP, is used as a purine substrate analogue in studies with enzymes such as Inosine monophosphate dehydrogenase (IMPDH); bacteriophage T4 RNA-ligase (EC 6.5.1.3) and pancreatic fibonuclease A.
Solubility
Soluble in water. (10.6 mg/mL)
Notes
Keep away from heat and humidity. Incompatible with strong oxidizing agents.
Specifications
| 6-Chloropurine riboside | |
| 158°C to 162°C (decomposition) | |
| C10H11ClN4O4 | |
| 5 g | |
| 6-chloropurine riboside, chloropurine riboside, 2r,3r,4s,5r-2-6-chloro-9h-purin-9-yl-5-hydroxymethyl tetrahydrofuran-3,4-diol, 6-chloropurine ribonucleoside, 6-chloropurine-9-riboside, 6-chloro-9-ribofuranosyl-9h-purine, 9h-purine, 6-chloro-9-ribofuranosyl, 6-chloropurineriboside, 6-chloro-9-beta-d-ribofuranosyl-9h-purine, 6-chloronebularine | |
| XHRJGHCQQPETRH-UHFFFAOYNA-N | |
| (2R,3R,4S,5R)-2-(6-chloropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol | |
| 93003 | |
| 98% |
| 5399-87-1 | |
| White | |
| MFCD00005738 | |
| 40573 | |
| Soluble in water. (10.6mg/mL) | |
| OCC1OC(C(O)C1O)N1C=NC2=C(Cl)N=CN=C12 | |
| 286.67 | |
| 286.67 | |
| Powder |
Chemical Identifiers
| 5399-87-1 | |
| 286.67 | |
| XHRJGHCQQPETRH-UHFFFAOYNA-N | |
| 93003 | |
| OCC1OC(C(O)C1O)N1C=NC2=C(Cl)N=CN=C12 |
| C10H11ClN4O4 | |
| MFCD00005738 | |
| 6-chloropurine riboside, chloropurine riboside, 2r,3r,4s,5r-2-6-chloro-9h-purin-9-yl-5-hydroxymethyl tetrahydrofuran-3,4-diol, 6-chloropurine ribonucleoside, 6-chloropurine-9-riboside, 6-chloro-9-ribofuranosyl-9h-purine, 9h-purine, 6-chloro-9-ribofuranosyl, 6-chloropurineriboside, 6-chloro-9-beta-d-ribofuranosyl-9h-purine, 6-chloronebularine | |
| (2R,3R,4S,5R)-2-(6-chloropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol |
Safety and Handling
EINECSNumber : 226-438-4
TSCA : No
storageNote1 : -30° to -10°C
Recommended Storage : Store at -20°C
RUO – Research Use Only