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6-Chloropurine riboside, 98%

CAS: 5399-87-1 | C10H11ClN4O4 | 286.67 g/mol

$208.30 - $617.86

Chemical Identifiers

CAS 5399-87-1
Molecular Formula C10H11ClN4O4
Molecular Weight (g/mol) 286.67
MDL Number MFCD00005738
InChI Key XHRJGHCQQPETRH-UHFFFAOYNA-N
Synonym 6-chloropurine riboside, chloropurine riboside, 2r,3r,4s,5r-2-6-chloro-9h-purin-9-yl-5-hydroxymethyl tetrahydrofuran-3,4-diol, 6-chloropurine ribonucleoside, 6-chloropurine-9-riboside, 6-chloro-9-ribofuranosyl-9h-purine, 9h-purine, 6-chloro-9-ribofuranosyl, 6-chloropurineriboside, 6-chloro-9-beta-d-ribofuranosyl-9h-purine, 6-chloronebularine
PubChem CID 93003
IUPAC Name (2R,3R,4S,5R)-2-(6-chloropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
SMILES OCC1OC(C(O)C1O)N1C=NC2=C(Cl)N=CN=C12
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AAH5963403
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Thermo Scientific Chemicals
H5963403
1 g
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AAH5963406
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Thermo Scientific Chemicals
H5963406
5 g
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Description

Description

6-Chloropurine riboside is used to study the kinetics and substrate specificity of adenosine deaminase. 6-Chloropurine riboside is benzoylated to facilitate synthesis of nucleoside derivatives such as 9-(2,3-Di-deoxy-2-fluoro-β-D-threo-pentofuranosyl)adenine. It , especially after phosphorylation to NMP, NDP or NTP, is used as a purine substrate analogue in studies with enzymes such as Inosine monophosphate dehydrogenase (IMPDH); bacteriophage T4 RNA-ligase (EC 6.5.1.3) and pancreatic fibonuclease A.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
6-Chloropurine riboside is used to study the kinetics and substrate specificity of adenosine deaminase. 6-Chloropurine riboside is benzoylated to facilitate synthesis of nucleoside derivatives such as 9-(2,3-Di-deoxy-2-fluoro-β-D-threo-pentofuranosyl)adenine. It , especially after phosphorylation to NMP, NDP or NTP, is used as a purine substrate analogue in studies with enzymes such as Inosine monophosphate dehydrogenase (IMPDH); bacteriophage T4 RNA-ligase (EC 6.5.1.3) and pancreatic fibonuclease A.

Solubility
Soluble in water. (10.6 mg/mL)

Notes
Keep away from heat and humidity. Incompatible with strong oxidizing agents.
Specifications

Chemical Identifiers

5399-87-1
286.67
XHRJGHCQQPETRH-UHFFFAOYNA-N
93003
OCC1OC(C(O)C1O)N1C=NC2=C(Cl)N=CN=C12
C10H11ClN4O4
MFCD00005738
6-chloropurine riboside, chloropurine riboside, 2r,3r,4s,5r-2-6-chloro-9h-purin-9-yl-5-hydroxymethyl tetrahydrofuran-3,4-diol, 6-chloropurine ribonucleoside, 6-chloropurine-9-riboside, 6-chloro-9-ribofuranosyl-9h-purine, 9h-purine, 6-chloro-9-ribofuranosyl, 6-chloropurineriboside, 6-chloro-9-beta-d-ribofuranosyl-9h-purine, 6-chloronebularine
(2R,3R,4S,5R)-2-(6-chloropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

Specifications

5399-87-1
White
MFCD00005738
40573
Soluble in water. (10.6mg/mL)
OCC1OC(C(O)C1O)N1C=NC2=C(Cl)N=CN=C12
286.67
286.67
Powder
158°C to 162°C (decomposition)
C10H11ClN4O4
1 g
6-chloropurine riboside, chloropurine riboside, 2r,3r,4s,5r-2-6-chloro-9h-purin-9-yl-5-hydroxymethyl tetrahydrofuran-3,4-diol, 6-chloropurine ribonucleoside, 6-chloropurine-9-riboside, 6-chloro-9-ribofuranosyl-9h-purine, 9h-purine, 6-chloro-9-ribofuranosyl, 6-chloropurineriboside, 6-chloro-9-beta-d-ribofuranosyl-9h-purine, 6-chloronebularine
XHRJGHCQQPETRH-UHFFFAOYNA-N
(2R,3R,4S,5R)-2-(6-chloropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
93003
98%
6-Chloropurine riboside
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Safety and Handling

Safety and Handling

EINECSNumber : 226-438-4

TSCA : No

storageNote1 : -30° to -10°C

Recommended Storage : Store at -20°C

SDS
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RUO – Research Use Only