missing translation for 'onlineSavingsMsg'
Learn More
Learn More
6-Azauridine
CAS: 54-25-1 | C8H11N3O6 | 245.191 g/mol
$243.62 - $951.49
Chemical Identifiers
| CAS | 54-25-1 |
|---|---|
| Molecular Formula | C8H11N3O6 |
| Molecular Weight (g/mol) | 245.191 |
| MDL Number | MFCD00006472 |
| InChI Key | WYXSYVWAUAUWLD-SHUUEZRQSA-N |
| Synonym | 6-azauridine, 6-azuridine, azauridine, azur, riboazauracil, riboazauratsil, 6-azauracil 1-riboside, ribo-azuracil, 6-azauracil riboside, 6-azur |
| PubChem CID | 5901 |
| ChEBI | CHEBI:35668 |
| IUPAC Name | 2-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazine-3,5-dione |
| SMILES | C1=NN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
|
AAJ6130903
|
Thermo Scientific Chemicals
J6130903 |
1 g |
Each for $243.62
|
|
|||||
|
AAJ6130906
|
Thermo Scientific Chemicals
J6130906 |
5 g |
Each for $951.49
|
|
|||||
Description
6-Azauridine can be applied in antiviral studies. 6-azauridine inhibits de novo pyrimidine synthesis and DNA synthesis and is converted intracellularly into mono, di, and triphosphate derivatives, which incorporate into RNA and inhibit protein synthesis. It is also used as an antineoplastic antimetabolite. It interferes with pyrimidine biosynthesis thereby preventing formation of cellular nucleic acids. As the triacetate, it is also effective as an antipsoriatic.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications6-Azauridine can be applied in antiviral studies. 6-azauridine inhibits de novo pyrimidine synthesis and DNA synthesis and is converted intracellularly into mono, di, and triphosphate derivatives, which incorporate into RNA and inhibit protein synthesis. It is also used as an antineoplastic antimetabolite. It interferes with pyrimidine biosynthesis thereby preventing formation of cellular nucleic acids. As the triacetate, it is also effective as an antipsoriatic.
Solubility
It is soluble in water.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C
Chemical Identifiers
| 54-25-1 | |
| 245.191 | |
| WYXSYVWAUAUWLD-SHUUEZRQSA-N | |
| 5901 | |
| 2-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazine-3,5-dione |
| C8H11N3O6 | |
| MFCD00006472 | |
| 6-azauridine, 6-azuridine, azauridine, azur, riboazauracil, riboazauratsil, 6-azauracil 1-riboside, ribo-azuracil, 6-azauracil riboside, 6-azur | |
| CHEBI:35668 | |
| C1=NN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O |
Specifications
| 54-25-1 | |
| White | |
| MFCD00006472 | |
| 14,904 | |
| It is soluble in water. | |
| C1=NN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O | |
| 245.191 | |
| CHEBI:35668 | |
| Powder |
| 160°C to 161°C | |
| C8H11N3O6 | |
| 1 g | |
| 6-azauridine, 6-azuridine, azauridine, azur, riboazauracil, riboazauratsil, 6-azauracil 1-riboside, ribo-azuracil, 6-azauracil riboside, 6-azur | |
| WYXSYVWAUAUWLD-SHUUEZRQSA-N | |
| 2-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazine-3,5-dione | |
| 5901 | |
| 245.19 | |
| 6-Azauridine |
Safety and Handling
GHS H Statement
H351-H302-H312-H332
Suspected of causing cancer.
Harmful if swallowed.
Harmful in contact with skin.
Harmful if inhaled.
P201-P202-P261-P264b-P270-P271-P281-P301+P312-P302+P352-P304+P340-P308+P313-P312-P330-P363-P501c
H302+H312+H332-H351
EINECSNumber : 200-199-6
RTECSNumber : XY8575000
TSCA : No
Recommended Storage : Keep cold
RUO – Research Use Only