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3-(Trimethylsilyl)propargyl alcohol, 98%

CAS: 5272-36-6 | C6H12OSi | 128.25 g/mol

Supplier:  Thermo Scientific Chemicals L0964914

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Catalog No. AAL0964914


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Description

Description

3-(Trimethylsilyl)propargyl alcohol is used as a reagent to synthesize Isbogrel, a Thromboxane A 2 (TXA 2) synthase inhibitor and also a TXA 2 receptor antagonist that has potential to treat asthma.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
3-(Trimethylsilyl)propargyl alcohol is used as a reagent to synthesize Isbogrel, a Thromboxane A 2 (TXA 2) synthase inhibitor and also a TXA 2 receptor antagonist that has potential to treat asthma.

Solubility
Not miscible with water.

Notes
Moisture Sensitive. Store away from moisture and oxidizing agents. Protect from heat. Store under dry inert gas. Protect from humidity and water. Incompatible with oxidizing agents, heat and moisture.
Specifications

Specifications

170°C to 172°C
5272-36-6
C6H12OSi
MFCD00002913
1902505
3-trimethylsilyl-2-propyn-1-ol, 3-trimethylsilyl propargyl alcohol, 2-propyn-1-ol, 3-trimethylsilyl, 3-trimethylsilyl prop-2-yn-1-ol, 1-trimethylsilylpropargyl alcohol, acmc-209l1b, 3-trimethylsilylpropargyl alcohol, 3-trimethylsilanyl-prop-2-yn-1-ol, 3-trimethylsilyl-2-propyn-1-ol #
ZVGCJDPEKKEYES-UHFFFAOYSA-N
3-trimethylsilylprop-2-yn-1-ol
78930
≥98%
Moisture sensitive
3-(Trimethylsilyl)propargyl alcohol
25 g
(CH3)3SiC≡CCH2OH
UN2810
66°C (150°F)
Not miscible with water.
C[Si](C)(C)C#CCO
128.25
128.25
1.451
0.865

Chemical Identifiers

5272-36-6
128.25
ZVGCJDPEKKEYES-UHFFFAOYSA-N
78930
C[Si](C)(C)C#CCO
C6H12OSi
MFCD00002913
3-trimethylsilyl-2-propyn-1-ol, 3-trimethylsilyl propargyl alcohol, 2-propyn-1-ol, 3-trimethylsilyl, 3-trimethylsilyl prop-2-yn-1-ol, 1-trimethylsilylpropargyl alcohol, acmc-209l1b, 3-trimethylsilylpropargyl alcohol, 3-trimethylsilanyl-prop-2-yn-1-ol, 3-trimethylsilyl-2-propyn-1-ol #
3-trimethylsilylprop-2-yn-1-ol
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Safety and Handling

Safety and Handling

GHS H Statement
H301-H227-H315-H319-H335
Toxic if swallowed.
Combustible liquid.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

P210-P235-P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P370+P378q-P501c

H227-H315-H319-H335

DOTInformation : Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC, LIQUIDS, ORGANIC, N.O.S.

EINECSNumber : 226-094-5

TSCA : Yes

Recommended Storage : Keep cold

SDS
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