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siRNA

Small interfering RNA/silencing RNA (siRNA) is a class of double-stranded, non-coding RNA molecule, 20-25 base pairs in length. As part of the RNA interference pathway, it regulates gene expression by degrading mRNA after transcription, preventing translation.
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1 – 15 de 53 résultats
2

Invitrogen™ Silencer™ Human Apoptosis siRNA Library  DFS Item

The Silencer™ Human Apoptosis siRNA Library provides investigators with a focused siRNA screening platform targeting apoptosis genes and enabling a detailed analysis of the apoptotic signaling pathway.

3

Invitrogen™ Silencer™ Human Tumor Suppressor siRNA Library  DFS Item

Mutations that cause a loss or reduction in gene function can result in the progression to cancer, usually in combination with other genetic changes. Tumor suppressor genes, or anti-oncogenes, can protect cells on the path to becoming cancerous.

4

Invitrogen™ Silencer™ Select Human Cell Cycle Regulation siRNA Library  DFS Item

Proteins that regulate cell division are crucial for controlling cell growth and are therefore potentially important drug targets.

5

Invitrogen™ Silencer™ Select Human Drug Targets siRNA Library  DFS Item

The Silencer™ Select Human Drug Targets siRNA Library contains 23,778 Ambion™ Silencer Select highly potent and chemically-modified siRNAs targeting 7,926 genes for performing RNAi screens against known human drug target genes.

RNAi Type siRNA
Pureté Standard
Type de produit siRNA Library
Gamme de produits Silencer™Select
Espèces Human
Conditions d’expédition Approved for shipment at Room Temperature or on Wet Ice
À utiliser avec (application) RNAi
6

Invitrogen™ Silencer™ Human Drug Targets siRNA Library  DFS Item

The Silencer™ Human Drug Targets siRNA Library includes genes involved in apoptosis, senescence, nucleic acid binding, autophagy, DNA repair, and along with characterized nuclear receptors and other genes that are considered potential targets for therapeutics.

RNAi Type siRNA
Pureté Standard
Type de produit siRNA Library
Gamme de produits Silencer
Type d’échantillon DNA
Espèces Human
Conditions d’expédition Approved for shipment at Room Temperature or on Wet Ice
À utiliser avec (application) RNAi
7

Invitrogen™ Silencer™ Human Phosphatase siRNA Library  DFS Item

Phosphatases are important regulators of biological pathways and cell signaling cascades.

8

Invitrogen™ Silencer™ Human Protease siRNA Library  DFS Item

Proteases are molecules that play an important role in many normal biological processes and have been implicated in different human diseases.

9

Ambion™ Silencer™ Validated siRNA  DFS Item

Silencer™ Select siRNAs are classic 21-mers which incorporate the latest improvements in siRNA design, off-target effect prediction algorithms, and chemistry.

RNAi Type siRNA
Description Silencer™ Validated siRNA
Gamme de produits Silencer
12

Invitrogen™ Silencer™ Human DNA Damage Response siRNA Library  DFS Item

DNA surveillance proteins monitor DNA integrity, and they can activate cell cycle checkpoints and DNA repair pathways in response to DNA damage. This can prevent potentially deleterious mutations.

13

Invitrogen™ Silencer™ Select Human Nuclear Hormone Receptor siRNA Library V4  DFS Item

For the first time, you can obtain the benefits of Ambion™Silencer™ Select siRNAs in a convenient pre-plated, library format.

14

Invitrogen™ Silencer™ Human Cell Cycle Regulation siRNA Library  DFS Item

Proteins that regulate cell division are crucial for controlling cell growth and are therefore potentially important drug targets.

15

Invitrogen™ Silencer™ Human Nuclear Hormone Receptor siRNA Library  DFS Item

The nuclear hormone receptor gene family includes receptors for thyroid and steroid hormones, retinoids and vitamin D, as well as receptors of unknown ligands.