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Ambion™ Silencer™ Select Pre-Designed siRNA DFS Item

Silencer™ Select Pre-Designed siRNA

Supplier:  Ambion™ 4390824

 View more versions of this product

Catalog No. 43-908-24



The Silencer™ Select siRNAs are classic 21-mers which incorporate the latest improvements in siRNA design, off-target effect prediction algorithms, and chemistry. A choice of Silencer™ Select siRNAs are available—Pre-Designed or Validated. Silencer™ Select Pre-Designed siRNAs are guaranteed-to-silence based on their proven design while the Silencer™ Select Validated siRNAs are functionally tested to reduce target gene expression. Sets of Silencer™ Select siRNA Libraries are also available in tubes or plate for high throughput screening. The Silencer™ Select Positive and Negative Control RNAs should be included in every siRNA experiment.

The benefits of using Silencer™ Select siRNAs include:
  • Potent—up to 100-fold more potent than currently available siRNAs and fewer off-target effects
  • Most Specific—LNA™ chemical modifications reduce off-target effects by up to 90%
  • Reliable—demonstrated improvements in consistency and reliability of phenotypic results
  • Guaranteed—100% guaranteed to silence, the best guarantee in the industry

  • Note: Silencer™ Pre-Designed & Validated siRNAs are designed using our first-generation algorithm and DO NOT include any chemical modifications. They are recommended for completing in vitro RNAi studies that were started using Silencer™ siRNAs. For new studies we recommend Silencer Select siRNAs.

    Approximate Turnaround Times*
  • Standard purification: 4 business days
  • HPLC purification: 6 business days (20 and 40 nmol); 15 business days (250 nmol)
  • In Vivo Ready: 15 business days (250 nmol)
  • Specifications


    Contains dried siRNA at (5 nmol) and Nuclease-free Water (1.75 mL), shipped at ambient temperature. Upon receipt, store siRNAs in a non-frost-free freezer at or below –20 °.
    RNAi, epigenetics and non-coding RNA research, RNAi, siRNA
    Silencer™ Select validated siRNA
    5 nmol
    Silencer™ Select Validated siRNA, 5nmol, Standard Purity, For RNAi, epigenetics and Non-Coding RNA research, RNAi, siRNA
    Silencer™ Select validated siRNA
    Silencer™ Select, Ambion™
    Standard purity




    For Research Use Only. Not for use in diagnostic procedures.