missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. FEPA5144639

Invitrogen™ YTHDF2 Polyclonal Antibody
GREENER_CHOICE

Catalog No. FEPA5144639
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
FEPA5144639 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. FEPA5144639 Supplier Invitrogen™ Supplier No. PA5144639
Only null left

Description

Rabbit Polyclonal Antibody

Positive control: 293T cell lysate, PC-12 cell lysate, NIH/3T3 cell lysates, NIH/3T3. Predicted band size: 62 kDa Subcellular Location: Nucleus, cytosol.

Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. Acts as a regulator of mRNA stability: binding to m6A-containing mRNAs results in the localization to mRNA decay sites, such as processing bodies (P-bodies), leading to mRNA degradation. Also acts as a promoter of cap-independent mRNA translation following heat shock stress: upon stress, relocalizes to the nucleus and specifically binds mRNAs with some m6A methylation mark at their 5'-UTR, protecting demethylation of mRNAs by FTO, thereby promoting cap-independent mRNA translation.

Specifications

Antigen YTHDF2
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene YTHDF2
Gene Accession No. Q91YT7, Q9Y5A9
Gene Alias 9430020E02Rik; CAHL; CLL-associated antigen KW-14; HGRG8; high glucose-regulated protein 8; high-glucose-regulated protein 8; LOW QUALITY PROTEIN: YTH domain-containing family protein 2; NY-REN-2; renal carcinoma antigen NY-REN-2; YTH domain family 2; YTH domain family protein 2; YTH domain family, member 2; YTH domain-containing family protein 2; YTH N(6)-methyladenosine RNA binding protein 2; YTH N6-methyladenosine RNA binding protein 2; yth2; YTHDF2; zgc:56224
Gene Symbols YTHDF2
Host Species Rabbit
Immunogen Recombinant protein within Full length of Human YTHDF2.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 213541, 313053, 51441
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less