missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Invitrogen™ WIPI2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA554098
Description
Immunogen sequence: ECALMKQHRL DGSLETTNEI LDSASHDCPL VTQTYGAAAG KGTYVPSSPT RLAYTDDLGA VGGACLEDEA SALRLDEDSE HPPMILRTD Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 84%.
WD repeat proteins play a role in many essential biologic functions, regulating the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. WIPI2, also known as ATG18B or ATG21, is a human homolog to yeast ATG18 and contains three WD repeats and has a 7-bladed propeller structure with a conserved motif that facilitates its interaction with other proteins. It is recruited to early autophagosomal structures along with Atg16L and ULK1 and is required for the formation of LC3-positive autophagosomes. Along with the highly related WIPI1, WIPI2 is found at the plasma membrane in addition to autophagosomal membranes.Specifications
| WIPI2 | |
| Polyclonal | |
| Unconjugated | |
| WIPI2 | |
| 1110018O08Rik; 2510001I10Rik; ATG18B; Atg21; CGI-50; WD repeat domain phosphoinositide-interacting protein 2; WD repeat domain, phosphoinositide interacting 2; WD40 repeat protein interacting with phosphoinositides 2; WIPI2; WIPI-2; WIPI49-like protein 2 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 26100, 288498, 74781 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 0.4 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q6AY57, Q80W47, Q9Y4P8 | |
| WIPI2 | |
| Recombinant protein corresponding to Human WIPI2. Recombinant protein control fragment (Product #RP-92773). | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |