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Invitrogen™ WDR5 Recombinant Human Monoclonal Antibody (RAB-C223)
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Catalog No. MA551835
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100 μg
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Catalog No. Quantity
MA551835 100 μg
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Catalog No. MA551835 Supplier Invitrogen™ Supplier No. MA551835
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Description

Human Recombinant Monoclonal Antibody

This antibody recognizes WDR5 (WD repeat-containing protein 5). It binds to a folded domain, amino acids 1-334. WDR5 is a protein that is involved in histone modification.

Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway.

Specifications

Antigen WDR5
Applications ChIP Assay, ELISA, Flow Cytometry, Immunoprecipitation, Immunocytochemistry
Classification Recombinant Monoclonal
Clone RAB-C223
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% ProClin 300
Gene WDR5
Gene Accession No. P61964
Gene Alias 2410008O07Rik; AA408785; AA960360; Big; BIG3; BIG-3; BMP2-induced 3-kb gene protein; CFAP89; cilia and flagella associated protein 89; SWD3; SWD3, Set1c WD40 repeat protein, homolog; Unknown (protein for MGC:137327); WD repeat domain 5; WD repeat-containing protein 5; WD repeat-containing protein BIG-3; Wdr5; wu:fk47f04; zgc:56591; zgc:76895; zgc:76895 protein
Gene Symbols WDR5
Host Species Human
Immunogen This antibody was obtained by recombinant antibody (rAb) phage display recognizing WDR5 protein under non-denaturing conditions.
Purification Method Metal-chelate chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11091
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype F(ab) κ
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