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Invitrogen™ Vivofectamine™ VF232 Liver LNP Composition in Ethanol

Catalog No. VF232LVCE
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VF232LVCE 1 mL
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Catalog No. VF232LVCE Supplier Invitrogen™ Supplier No. VF232LVCE
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Description

Vivofectamine VF232 Liver LNP Composition in Ethanol is a reagent for use in the creation of lipid nanoparticles (LNPs) for in vivo delivery of mRNA or mRNA/gRNA via intravenous (IV) route to the liver.

Vivofectamine VF232 Liver LNP Composition in Ethanol is a reagent for use in the creation of lipid nanoparticles (LNPs) for in vivo delivery of mRNA or mRNA/gRNA via intravenous (IV) route to the liver. It can be used for various basic research applications such as protein expression, protein replacement, and genome editing.

Features and benefits

  • Optimized formulation for systemic liver delivery
  • Delivery efficiency data in vivo benchmarked to ionizable lipids used in leading clinical-stage or FDA-approved drugs
  • Safety characterization in vivo
  • Flexibility in choice of formulation device and method

Vivofectamine VF232 Liver LNP Composition in Ethanol is a pre-mixed solution with an optimized ratio of an ionizable lipid and helper lipids. It can be used with various formulation devices and methods.

Vivofectamine VF232 Liver LNP Composition in Ethanol is a Research Use Only reagent for use in basic research. For an LNP solution for drug development purposes with a path to clinical and commercial licensing and supply, please submit a contact us request at our Vivofectamine webpage to access our Vivofectamine Delivery Solutions Drug Developers Portfolio.

Vivofectamine VF232 Liver LNP Composition in Ethanol is an animal origin-free product.

Specifications

Classification Animal origin-free (AOF)
Delivery Type In vivo
Format Tube
Transfection Technique Lipid-based Transfection, Lipid Nanoparticles, LNPs
Species Mouse
Formulation Ratio-optimized mixture of lipid solution in ethanol
Product Line Vivofectamine
Product Type Reagent
Quantity 1 mL
Shipping Condition Dry Ice
Sterility Non-sterile
Target Liver
Sufficient For Encapsulating up to 0.6 mg mRNA at N:P of 4 (yield is dependent on formulation process)
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For Research Use Only. Not for use in diagnostic procedures.