missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Invitrogen™ VHL Polyclonal Antibody
Goat Polyclonal Antibody
Supplier: Invitrogen™ PA518549
Description
This antibody is predicted to react with canine based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.
Von Hippel-Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of this gene is the basis of familial inheritance of VHL syndrome. The protein encoded by this gene is a component of the protein complex that includes elongin B, elongin C, and cullin-2, and possesses ubiquitin ligase E3 activity. This protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF), which is a transcription factor that plays a central role in the regulation of gene expression by oxygen. RNA polymerase II subunit POLR2G/RPB7 is also reported to be a target of this protein. Alternatively spliced transcript variants encoding distinct isoforms have been observed.Chemical Identifiers
| VHL | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Polyclonal | |
| Liquid | |
| IgG | |
| Human, Mouse, Rat | |
| VHL | |
| elongin binding protein; HRCA1; Protein G7; pVHL; RCA1; VHL; VHL1; VHL19; Vhlh; VHLp18(MEA); Von Hippel Lindau; von hippel-lindau; von Hippel-Lindau disease tumor suppressor; von Hippel-Lindau syndrome homolog; von Hippel-Lindau syndrome protein homolog; von Hippel-Lindau tumor suppressor; von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase | |
| VHL | |
| Primary | |
| Ammonium sulfate precipitation |
| 0.5 mg/mL | |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| Unconjugated | |
| Goat | |
| RUO | |
| TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 | |
| P40337, P40338, Q64259 | |
| 22346, 24874, 7428 | |
| Synthetic peptide sequence (RSLVKPENYRRLD) corresponding to the internal amino acids of VHL (aa 167-179). | |
| Antibody |
Specifications
| VHL | |
| Polyclonal | |
| Unconjugated | |
| VHL | |
| elongin binding protein; HRCA1; Protein G7; pVHL; RCA1; VHL; VHL1; VHL19; Vhlh; VHLp18(MEA); Von Hippel Lindau; von hippel-lindau; von Hippel-Lindau disease tumor suppressor; von Hippel-Lindau syndrome homolog; von Hippel-Lindau syndrome protein homolog; von Hippel-Lindau tumor suppressor; von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase | |
| Goat | |
| Ammonium sulfate precipitation | |
| RUO | |
| 22346, 24874, 7428 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 0.5 mg/mL | |
| TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 | |
| P40337, P40338, Q64259 | |
| VHL | |
| Synthetic peptide sequence (RSLVKPENYRRLD) corresponding to the internal amino acids of VHL (aa 167-179). | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |