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(+/-)-Verapamil hydrochloride, 99+%

Catalog No. AAJ6153503
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Catalog No. AAJ6153503 Supplier Thermo Scientific Chemicals Supplier No. J6153503
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Description

CAS: 152-11-4 | C27H39ClN2O4 | 491.069 g/mol

±)-Verapamil hydrochloride is a calcium channel modulator, adrenoceptor antagonist, anti-arrhythmic, cardiac depressant, and coronary vasodilator. It is also a calcium channel-blocker. It acts by inhibiting the slow channel entry of calcium into the cell. It acts by plugging up the channels and limiting the entry of calcium into both smooth muscle cells of arteriolar walls and the cardiac muscle cells at higher doses.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
±)-Verapamil hydrochloride is a calcium channel modulator, adrenoceptor antagonist, anti-arrhythmic, cardiac depressant, and coronary vasodilator. It is also a calcium channel-blocker. It acts by inhibiting the slow channel e

Chemical Identifiers

CAS 152-11-4
Molecular Formula C27H39ClN2O4
Molecular Weight (g/mol) 491.069
MDL Number MFCD00055208
InChI Key DOQPXTMNIUCOSY-UHFFFAOYSA-N
Synonym verapamil hydrochloride, verapamil hcl, manidon, calcan hydrochloride, cardibeltin, cardiabeltin, cardioprotect, veroptinstada, calaptin, caveril
PubChem CID 62969
IUPAC Name 2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile;hydrochloride
SMILES CC(C)C(CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)OC)OC.Cl

Specifications

Melting Point 138°C to 141°C
Color White
Quantity 1 g
UN Number UN2811
Beilstein 3647093
Merck Index 14,9950
Solubility Information Soluble in water; Also soluble in ethanol or methanol
Formula Weight 491.07
Percent Purity ≥99%
Physical Form Powder
Chemical Name or Material (+/-)-Verapamil hydrochloride
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Safety and Handling

Hazard Category H301+H311+H331
Hazard Statement GHS H Statement
H301-H311-H331
Toxic if swallowed.
Toxic in contact with skin.
Toxic if inhaled.
Precautionary Statement P260-P264b-P270-P271-P280-P301+P310-P302+P352-P304+P340-P311-P312-P314-P330-P361-P363-P501c
DOTInformation Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.
EINECSNumber 205-800-5
RTECSNumber YV8320000
TSCA No
Recommended Storage Ambient temperatures

RUO – Research Use Only