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Invitrogen™ Venezuelan Equine Encephalitis Virus NSP1 Recombinant Rabbit Monoclonal Antibody (HL1472)
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Catalog No. pima547057
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100 μL
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PIMA547057 100 μL
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Catalog No. PIMA547057 Supplier Invitrogen™ Supplier No. MA547057
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Description

Rabbit Recombinant Monoclonal Antibody

Store as concentrated solution. Centrifuge briefly prior to opening vial.

Venezuelan equine encephalitis virus (VEEV) is a member of genus Alphavirus in the family Togaviridae VEEV encodes four nonstructural proteins (nsP1, nsP2, nsP3 and nsP4) and five structural proteins (capsid (C), envelope (E) 3, E2, 6k, and E1) The Nsp1 gene of VEEV contains a 51-nt conserved sequence element (CSE) that is essential for virus replication Mutation or deletion of CSE results in loss of infectivity of VEEV, probably due to inefficient recognition of the viral RNA core promoter element by the virus replication complex Nsp1 functions as a methyltransferase and guanylylation enzyme, two properties needed for the 5' capping of VEEV genomic RNA [PMID: 30781656].

Specifications

Antigen Venezuelan Equine Encephalitis Virus NSP1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone HL1472
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene Alias VEEV NSP1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the N-term region of Venezuelan equine encephalitis virus nsp1. The exact sequence is proprietary.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Target Species Virus
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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