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Invitrogen™ VE-cadherin Monoclonal Antibody (BV9)
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Catalog No. PIMA1198
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100 μg
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Catalog No. Quantity
PIMA1198 100 μg
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Catalog No. PIMA1198 Supplier Invitrogen™ Supplier No. MA1198

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Description

Mouse Monoclonal Antibody

MA1-198 VE-Cadherin antibody detects human VE-cadherin by western blot, immunofluorescence and flow cytometry. This monoclonal antibody recognizes the extracellular domain of the VE-cadherin protein which is highly expressed at intercellular junctions of vascular endothelial cells such as Huvec.

VE-cadherin is a member of the cadherin superfamily that is located in a six-cadherin cluster in a region on the long arm of chromosome 16 and is involved in loss of heterozygosity events in breast and prostate cancer. VE-cadherin protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, VE-cadherin may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but the full length sequence of VE-cadherin has not been determined.

Specifications

Antigen VE-cadherin
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone BV9
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1mg/mL BSA and 0.05% sodium azide
Gene CDH5
Gene Accession No. P33151
Gene Alias 7B4; 7B4 antigen; 7B4/cadherin-5; AA408225; cadherin 5; cadherin 5, type 2 (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular epithelium); cadherin-5; cadherin-5; cd144 antigen; VE cadherin; Cd144; cd144 antigen; CDH5; cell-cell adhesion protein; endothelial-specific cadherin; vascular endothelial cadherin; vascular endothelial cadherin precursor; Vec; VEcad; VE-Cad; VE-cadherin; VECD
Gene Symbols CDH5
Host Species Mouse
Immunogen Recombinant protein corresponding to the extracellular domain of human VE-Cadherin.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1003
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a
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