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Invitrogen™ VAV1 Monoclonal Antibody (1582CT802.383.58)
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Catalog No. pima537688
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Quantity:
200 μL
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Catalog No. Quantity
PIMA537688 200 μL
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Catalog No. PIMA537688 Supplier Invitrogen™ Supplier No. MA537688
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Description

Mouse Monoclonal Antibody

VAV1 Monoclonal Antibody for Western Blot

The VAV1 gene, located on chromosome 19p13.2, encodes for a protein that functions as a guanine nucleotide exchange factor (GEF). Structurally, the VAV1 protein contains several functional domains, including Dbl homology (DH) and pleckstrin homology (PH) domains, which facilitate its role in exchange activity, and SH3 and SH2 domains, critical for signal transduction. VAV1 is primarily expressed in hematopoietic cells and plays a crucial role in the regulation of immune responses, particularly in T-cell receptor signaling. It influences actin cytoskeleton reorganization, cell proliferation, and differentiation, making it vital for proper immune system function.

Specifications

Antigen VAV1
Applications Western Blot
Classification Monoclonal
Clone 1582CT802.383.58
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene VAV1
Gene Accession No. P15498
Gene Alias oncogene vav; p95; p95vav; Proto-oncogene vav; VAV; vav 1 guanine nucleotide exchange factor; vav 1 oncogene; vav guanine nucleotide exchange factor 1; vav oncogene; vav proto-oncogene; VAV1; vav-T
Gene Symbols VAV1
Host Species Mouse
Immunogen recombinant protein of human VAV1.
Purification Method Protein G
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7409
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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