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Invitrogen™ USP34 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5104200
Description
Antibody detects endogenous levels of total USP34.
Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin (CTNBB1)-mediated transcription. Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.Specifications
| USP34 | |
| Polyclonal | |
| Unconjugated | |
| USP34 | |
| A530081C03Rik; deubiquitinating enzyme 34; KIAA0570; KIAA0729; Murr2; U2af1-rs1 region 2; ubiquitin carboxyl-terminal hydrolase 34; ubiquitin specific peptidase 34; ubiquitin specific protease 34; ubiquitin thioesterase 34; ubiquitin thiolesterase 34; ubiquitin-specific-processing protease 34; Usp34 | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 17847, 9736 | |
| -20°C | |
| Liquid |
| Western Blot | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| Q6ZQ93, Q70CQ2 | |
| USP34 | |
| A synthesized peptide derived from human USP34(Accession Q70CQ2), corresponding to amino acid residues S516-D566. | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |