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Invitrogen™ UBE2D1 Monoclonal Antibody (07)
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Catalog No. PIMA536014
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100 μL
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Catalog No. Quantity
PIMA536014 100 μL
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Catalog No. PIMA536014 Supplier Invitrogen™ Supplier No. MA536014
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Description

Mouse Monoclonal Antibody

UBE2D1 Monoclonal Antibody for Flow

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases.

Specifications

Antigen UBE2D1
Applications Flow Cytometry
Classification Monoclonal
Clone 07
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene UBE2D1
Gene Accession No. P51668
Gene Alias (E3-independent) E2 ubiquitin-conjugating enzyme D1; E2 ubiquitin-conjugating enzyme D1; E2(17)KB 1; E2(17)KB1; SFT; Stimulator of Fe transport; UBC 4/5; UBC4/5; UBC4/5 homolog; UBC5A; UBCH 5; UBCH 5A; UBCH5; UBCH5A; UBE2D1; ubiquitin; Ubiquitin carrier protein D1; ubiquitin conjugating enzyme E2 D1; ubiquitin conjugating enzyme E2D 1; ubiquitin-conjugating enzyme E2 D1; Ubiquitin-conjugating enzyme E2(17)KB 1; ubiquitin-conjugating enzyme E2-17 kDa 1; ubiquitin-conjugating enzyme E2D 1; ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast); ubiquitin-conjugating enzyme E2D 1, UBC4/5 homolog; ubiquitin-protein ligase D1
Gene Symbols UBE2D1
Host Species Mouse
Immunogen Recombinant Human UBE2D1 Protein.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7321
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a
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