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Invitrogen™ TRIP10 Recombinant Rabbit Monoclonal Antibody (23GB4705)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA553791

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Catalog No. MA553791


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Description

Description

TRIP10 Recombinant Monoclonal Antibody for Western Blot, ICC/IF, Flow

Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling. Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.
Specifications

Specifications

TRIP10
Recombinant Monoclonal
Unconjugated
Trip10
AI646975; Cdc42 interacting protein-4; cdc42-interacting protein 4; Cip4; hSTP; protein Felic; Salt tolerant protein; salt tolerator; STOT; STP; thyroid hormone receptor interactor 10; thyroid receptor-interacting protein 10; TR-interacting protein 10; TRIP10; TRIP-10
Rabbit
Affinity chromatography
RUO
106628
-20°C
Liquid
Flow Cytometry, Western Blot, Immunocytochemistry
23GB4705
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Q8CJ53
Trip10
A synthesized peptide derived from human Cip4 (1-34AA).
20 μL
Primary
Mouse
Antibody
IgG
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