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Invitrogen™ TRIM Monoclonal Antibody (TRIM-04)
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA119283
Description
This antibody recognizes an intracellular epitope of T cell receptor-interacting molecule (TRIM), a 30 kDa adaptor protein expressed by T cells. This antibody will not cross-react with mouse. Western Blot: non-reducing conditions.
TRIM (T cell receptor-interacting molecule), also known as TRAT1 (T cell receptor associated transmembrane adaptor 1) is a 30 kDa protein expressed by T cells as a cystein-linked homodimer. It associates with TCR-CD3-zeta-chain complex and becomes phosphorylated by Src-family kinases. TRIM is potentially involved in negative regulation of TCR-mediated signaling, but its role remains unclear.Specifications
| TRIM | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 15mM sodium azide; pH 7.4 | |
| Q6PIZ9 | |
| TRAT1 | |
| Recombinant intracellular domain (aa 29-186) of human TRIM. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG2a |
| Flow Cytometry, Immunoprecipitation, Western Blot | |
| TRIM-04 | |
| Unconjugated | |
| TRAT1 | |
| C030046M14Rik; HSPC062; pp29/30; T cell receptor associated transmembrane adaptor 1; T cell receptor interacting molecule; T-cell receptor interacting molecule; T-cell receptor-associated transmembrane adapter 1; T-cell receptor-interacting molecule; TCRIM; Trat1; TRIM | |
| Mouse | |
| Protein A | |
| RUO | |
| 50852 | |
| 4°C, do not freeze | |
| Liquid |