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Invitrogen™ TRAP1 Monoclonal Antibody (3H4-2H6), APC
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA545308
Description
1 μg/mL of MA5-45308 was sufficient for detection of Trap-1/HSP75 in 20 μg of Human A431 lysate by ECL immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody. Detects approximately 75kDa.
The 90 kDa heat shock protein (hsp90) family of molecular chaperones is a highly conserved family of proteins that play an important physiological role. Hsp90 is involved in numerous cellular processes but is best known for its association with signal transduction machinery. A recently cloned homolog of hsp90 is the tumor necrosis factor receptor-associated protein (TRAP1). Like hsp90, TRAP1 is found to be associated with numerous proteins involved in diverse actions. Immunofluorescence data has shown TRAP1 to be localized in the mitochondria of mammalian cells. This observation and the fact that TRAP1 is shown to have a mitochondrial targeting presequence strongly implicates TRAP1 as a mitochondrial matrix protein.Specifications
| TRAP1 | |
| Monoclonal | |
| 1 mg/mL | |
| 2.48mM MES, 95.64mM phosphate with 0.5M EDTA and no preservative; pH 7.4 | |
| Q12931, Q5XHZ0, Q9CQN1 | |
| Trap1 | |
| Purified recombinant TRAP1. | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG1 κ |
| Western Blot, Immunocytochemistry | |
| 3H4-2H6 | |
| APC | |
| Trap1 | |
| 2410002K23Rik; heat shock protein 75 kDa, mitochondrial; HSP 75; HSP75; HSP90L; testicular tissue protein Li 209; TNF receptor associated protein 1; TNF receptor-associated protein 1; TNFR-associated protein 1; TRAP1; TRAP-1; tumor necrosis factor type 1 receptor associated protein; tumor necrosis factor type 1 receptor-associated protein | |
| Mouse | |
| Protein G | |
| RUO | |
| 10131, 287069, 68015 | |
| 4°C | |
| Liquid |