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Invitrogen™ TRAIL-R4 Polyclonal Antibody
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Catalog No. PIPA589612
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PIPA589612 100 μL
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Catalog No. PIPA589612 Supplier Invitrogen™ Supplier No. PA589612
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: VLFRRRSCPS RVPGAEDNAR NETLSNRYLQ PTQVSEQEIQ GQELAELTGV TVELPEEPQR LLEQAEAEGC QRRRLLVPVN DADSADISTL LDASATLEEG HAKETIQDQL VGSEKLFYEE DEAGSATSCL; Positive Samples: 22Rv1, Rat testis; Cellular Location: Membrane, Single-pass type I membrane protein.

TRAIL (also known as Apo-2L) is a member of the tumor necrosis factor (TNF) ligand family that rapidly induces apoptosis in a variety of transformed cell lines. A fourth member of the emerging TRAIL receptor family, TRAIL-R4, has signaling capacity similar to that of TRAIL-R1 and TRAIL-R2 with respect to NF-kappaB activation, but differs in its inability to induce apoptosis. Like TRAIL-R1 and TRAIL-R2, this receptor shows widespread tissue expression. The human TRAIL-R4 gene has been mapped to chromosome 8p22-21, clustered with three other TRAIL receptors.

Specifications

Antigen TRAIL-R4
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.78 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene TNFRSF10D
Gene Accession No. Q9UBN6
Gene Alias CD264; DCR2; Decoy receptor 2; TNF receptor superfamily member 10d; TNF receptor-related receptor for TRAIL; TNF-related apoptosis-inducing ligand receptor 4; TNFRSF10D; TRAIL receptor 4; TRAIL receptor with a truncated death domain; TRAILR4; TRAIL-R4; TRUNDD; Tumor necrosis factor receptor superfamily member 10D; tumor necrosis factor receptor superfamily member 10d, decoy with truncated death domain; tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain; UNQ251/PRO288
Gene Symbols TNFRSF10D
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 257-386 of human TNFRSF10D (NP_0038312).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8793
Target Species Human, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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