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Invitrogen™ Torc1 Monoclonal Antibody (2D4)
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA524872
Description
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells. In the hippocampus, involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses. May be required for dendritic growth of developing cortical neurons. In concert with SIK1, regulates the light-induced entrainment of the circadian clock. In response to light stimulus, coactivates the CREB-mediated transcription of PER1 which plays an important role in the photic entrainment of the circadian clock. [UniProt].Chemical Identifiers
| Torc1 | |
| 1 mg/mL | |
| Western Blot | |
| Unconjugated | |
| Mouse | |
| RUO | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q157S1, Q68ED7, Q6UUV9 | |
| 23373, 382056, 684527 | |
| Recombinant full length Human TORC1. | |
| Antibody |
| 2D4 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Monoclonal | |
| Liquid | |
| IgM | |
| Human, Mouse, Rat, Monkey | |
| CRTC1 | |
| AI413414; CH211-255D18.10; CH211-255D18.9; CREB regulated transcription coactivator 1; CREB regulated transcription coactivator 1b; CREB-regulated transcription coactivator 1; CREB-regulated transcription coactivator 1; CREB-regulated transcription coactivator 1b; CRTC1; crtc1b; FLJ14027; KIAA0616; MECT 1; Mect1; mKIAA0616; mucoepidermoid carcinoma translocated 1; mucoepidermoid carcinoma translocated protein 1; Mucoepidermoid carcinoma translocated protein 1 homolog; R74955; si:ch211-255d18.8; TORC1; TORC-1; transducer of CREB protein 1; transducer of regulated cAMP response element-binding protein (CREB) 1; transducer of regulated cAMP response element-binding protein 1; WAMTP1; zfTorc1 | |
| CRTC1 | |
| Primary | |
| Antigen affinity chromatography |
Specifications
| Torc1 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q157S1, Q68ED7, Q6UUV9 | |
| CRTC1 | |
| Recombinant full length Human TORC1. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat, Monkey | |
| Antibody | |
| IgM |
| Western Blot | |
| 2D4 | |
| Unconjugated | |
| CRTC1 | |
| AI413414; CH211-255D18.10; CH211-255D18.9; CREB regulated transcription coactivator 1; CREB regulated transcription coactivator 1b; CREB-regulated transcription coactivator 1; CREB-regulated transcription coactivator 1; CREB-regulated transcription coactivator 1b; CRTC1; crtc1b; FLJ14027; KIAA0616; MECT 1; Mect1; mKIAA0616; mucoepidermoid carcinoma translocated 1; mucoepidermoid carcinoma translocated protein 1; Mucoepidermoid carcinoma translocated protein 1 homolog; R74955; si:ch211-255d18.8; TORC1; TORC-1; transducer of CREB protein 1; transducer of regulated cAMP response element-binding protein (CREB) 1; transducer of regulated cAMP response element-binding protein 1; WAMTP1; zfTorc1 | |
| Mouse | |
| Antigen affinity chromatography | |
| RUO | |
| 23373, 382056, 684527 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |