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Tolmetin sodium salt dihydrate, 98+%

An NSAID compound | CAS: 64490-92-2 | C15H18NNaO5 | 315.301 g/mol

Supplier:  Thermo Scientific Chemicals J6266303

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Catalog No. AAJ6266303


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Description

Description

Tolmetin Sodium is an anti-inflammatory, antirheumatic agent. It can inhibit aldo-keto reductases (e.g., IC50 = 2.39 μM for human aldose reductase), a family of enzymes that catalyze the NADPH-dependent reduction of carbonyl groups in a number of important steroid, metabolic, and prostanoid molecules. It is a beta-adrenergic blocker.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Tolmetin Sodium is an anti-inflammatory, antirheumatic agent. It can inhibit aldo-keto reductases (e.g., IC50 = 2.39 µM for human aldose reductase), a family of enzymes that catalyze the NADPH-dependent reduction of carbonyl groups in a number of important steroid, metabolic, and prostanoid molecules. It is a beta-adrenergic blocker.

Solubility
Soluble in water

Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
Specifications

Specifications

Tolmetin sodium salt dihydrate
White
MFCD00150761
14,9518
Soluble in water
CC1=CC=C(C=C1)C(=O)C2=CC=C(N2C)CC(=O)[O-].O.O.[Na+]
315.301
CHEBI:72014
≥98%
64490-92-2
C15H18NNaO5
1 g
tolmetin sodium dihydrate, sodium tolmetin dihydrate, tolumetin sodium dihydrate, unii-02n1tzf99f, sodium 2-1-methyl-5-4-methylbenzoyl-1h-pyrrol-2-yl acetate dihydrate, tolmetin sodium salt dihydrate, sodium 1-methyl-5-p-toluoylpyrrole-2-acetate dihydrate, tolectin tn, 1-methyl-5-p-toluoyl pyrrole-2 acetic acid
QQILXENAYPUNEA-UHFFFAOYSA-M
sodium;2-[1-methyl-5-(4-methylbenzoyl)pyrrol-2-yl]acetate;dihydrate
23677829
315.30 (279.27 Anhydrous)
Powder

Chemical Identifiers

64490-92-2
315.301
QQILXENAYPUNEA-UHFFFAOYSA-M
23677829
sodium;2-[1-methyl-5-(4-methylbenzoyl)pyrrol-2-yl]acetate;dihydrate
C15H18NNaO5
MFCD00150761
tolmetin sodium dihydrate, sodium tolmetin dihydrate, tolumetin sodium dihydrate, unii-02n1tzf99f, sodium 2-1-methyl-5-4-methylbenzoyl-1h-pyrrol-2-yl acetate dihydrate, tolmetin sodium salt dihydrate, sodium 1-methyl-5-p-toluoylpyrrole-2-acetate dihydrate, tolectin tn, 1-methyl-5-p-toluoyl pyrrole-2 acetic acid
CHEBI:72014
CC1=CC=C(C=C1)C(=O)C2=CC=C(N2C)CC(=O)[O-].O.O.[Na+]
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Safety and Handling

Safety and Handling

GHS H Statement
H302-H315
Harmful if swallowed.
Causes skin irritation.

P264b-P270-P280-P301+P312-P302+P352-P305+P351+P338-P330-P332+P313-P362-P501c

H302-H315-H319

EINECSNumber : 252-687-3

RTECSNumber : UX9280000

TSCA : No

Recommended Storage : Ambient temperatures

SDS
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